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Senior Linux Systems Engineer

Ultimagenomics

Fremont, California, United States (Fremont, CA) permanent

Posted: October 8, 2025

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Job Description

Rapidly Growing Life Sciences Technology Company

Ultima Genomics is a rapidly growing company that is developing ground-breaking genomics technologies. Our mission is to continuously drive the scale of genomic information to enable unprecedented advances in biology and improvements in human health. We have developed a foundational new approach to sequencing at scale that overcomes limitations due to the high costs of current technologies. We are well-funded and have raised approximately $600 million from global top-tier investors. Our team brings together unique and diverse expertise across multiple disciplines, from healthcare and life sciences, to engineering, to technology and software and beyond. We are a collaborative group, including successful entrepreneurs, chemists, hardware and software engineers, genomics and biotechnology experts, molecular and computational biologists, software and algorithm experts, and operations and commercial leaders. Join us to develop and commercialize technologies that unleash the power of genomics at scale and empower the future of human health.

We are looking for a highly motivated Senior Linux Systems Engineer to join our Computing Team!

You will work on high-performance computing (HPC) systems that are part of our sequencing platform. The ideal candidate is a hands-on Linux expert who thrives on optimizing performance and building secure, scalable and reliable systems in a fast-paced environment.

This is a full-time, on-site position at our Fremont, CA headquarters.

How You’ll Contribute

• Design, build, and maintain high-performance Linux systems supporting compute and data-intensive workloads

• Optimize system performance through kernel and filesystem tuning; identify and eliminate I/O, memory, or network bottlenecks

• Automate provisioning and configuration management using orchestration tools such as Ansible and Salt

• Monitor and troubleshoot kernel, driver, and hardware issues; perform root cause analysis in partnership with data and engineering teams and propose long-term solutions

• Ensure system reliability through regular patching, monitoring, and performance tuning

• Maintain accurate system documentation, runbooks, and configuration baselines

• Collaborate with software, hardware, and scientific teams to ensure platform reliability and scalability

• Other duties as assigned

Qualifications, Skills, Knowledge & Abilities

• BS in Computer Science, Engineering, or related field

• 5+ years of experience designing and building high-performance physical Linux systems in high-throughput or mission-critical environments

• Deep knowledge of Linux kernel, NFS and Linux file system performance tuning

• Solid background in TCP/IP networking, routing, VLANs, and firewall rules

• Experience with the latest CPU and GPU technologies

• Proficiency in shell scripting (bash), working knowledge of Python, and familiarity with Ansible or similar configuration management tools

• Proven hands-on experience building servers from components, diagnosing hardware failures, and working with vendors

• Excellent documentation and communication skills

• May occasionally be exposed to activity that requires pulling/lifting/moving/carrying up to 50 lbs

• Experience with cloud computing infrastructure (e.g. AWS) and Docker desirable

• Familiarity with security frameworks and compliance standards (e.g. ISO 27001) a plus

At Ultima Genomics, your base pay is one part of your total compensation package. This role pays between $125,000 and $150,000, if performed in California, and your actual base pay will depend on your skills, qualifications, experience, and location. Please note that the compensation details listed in US role postings reflect the base salary only, and do not include bonus, equity, or benefits. This role is also eligible for a competitive benefits package that includes: medical, dental, vision, life, and disability insurance; 401(k) retirement plan; flexible spending & health savings account; paid holidays; paid time off; employee assistance program; and other company benefits.#LI-Onsite

Ultima Genomics is proud to be an equal opportunity workplace and is an affirmative action employer. We provide equal employment opportunity for all applicants and employees. We do not discriminate on the basis of race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), gender identity, gender expression, national origin, ancestry, citizenship, age, physical or mental disability, military or veteran status, marital status, domestic partner status, sexual orientation, genetic information, or any other basis protected by applicable laws. See also Ultima Genomics’ EEO Policy and Know Your Rights. If you have a disability or special need that requires accommodation, please let us know by contacting [email protected].

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