Reliability Engineer (On-Premise Focus)

This position is on-site in Philadelphia

About Proscia

Pathology is at the center of medicine, and is undergoing a profound transformation as the final frontier of digitization in healthcare. We started Proscia to accelerate pathology’s transition from microscope to images, and to use AI to change the way we think about cancer. We can’t change medicine alone. That’s why we’re looking for curious thinkers. Big dreamers. Developers, evangelists, pathologists, and scientists. Exceptional talent to help us use the great power of AI for good and advance humankind.

At Proscia, we push the limits of medicine and technology, solving problems the world has never solved before. We build software used by thousands of scientists and pathologists, who work on the front lines of fighting big enemies like cancer for patients around the globe. To accelerate our vision, Proscia has raised over $100M in capital from world-class healthcare and technology investors.

About This Position

As a Reliability Engineer, you will own the reliability, performance, and operational excellence of Proscia’s on-premise installations at customer sites. Our platform powers high-resolution digital pathology and AI-assisted workflows in clinical and research environments, often running on customer-managed infrastructure. You’ll ensure these deployments are stable, performant, secure, and continuously improving.

This is a hands-on role focused on on-premise container based deployments, systems performance, and real-world operational problem solving in complex customer environments.

What You’ll Do

Working at a startup like Proscia means wearing many hats, but when you come to work you can expect to focus on the following:

Deploy, configure, and support Proscia’s container based application stack in on-premise customer environments.

Own system reliability across customer installations, including uptime, performance, backup/recovery, and upgrade workflows.

Diagnose and resolve production incidents, performing deep root cause analysis across application, container, host, storage, and networking layers.

Optimize performance for large image datasets and AI workloads running on customer-managed compute infrastructure.

Improve installation automation, configuration management, and repeatability across diverse environments.

Develop and refine monitoring, logging, and alerting patterns appropriate for customer-hosted deployments.

Collaborate closely with Engineering, Customer Success, and Support to translate field learnings into product and operational improvements.

Document best practices and create operational playbooks for internal teams and customers.

Leverage AI tools (e.g., Claude, code assistants, automation frameworks) to streamline troubleshooting, scripting, and operational workflows.

What We’re Seeking

We’re looking for people who are smart, professional, & get stuff done. Proscia is a high-growth company, and we want entrepreneurial doers that thrive in a challenging environment, ready to build the plane while flying it. Proscia’s next Reliability Engineer will have:

Deep hands-on experience deploying and operating containerized applications using container tools such as Docker and Docker Compose in production environments.

Strong Linux systems expertise (process management, networking, storage, security hardening, performance tuning)

Expert troubleshooting skills in distributed systems across application, container, and infrastructure layers.

Experience in enterprise networking technologies, and the ability to troubleshoot and suggest corrections in customer infrastructure.
Familiarity with operating software in customer-managed or on-premise environments.

Experience supporting data-intensive systems, ideally involving large image files or compute-heavy workloads.

Working knowledge of observability practices (logs, metrics, tracing) and pragmatic monitoring approaches in non-cloud-native environments.

Comfort working directly with customers or customer-facing teams to resolve high-impact issues.

Demonstrated AI fluency: hands-on experience using tools like Claude, ChatGPT, GitHub Copilot, or similar AI systems to enhance productivity, automate tasks, and solve technical problems.

A mindset aligned with Proscia’s values: ownership, speed, simplification, and a willingness to challenge the status quo.

Nice to Have:

Experience with healthcare or regulated environments.

Exposure to Kubernetes (for hybrid or future-state deployments).

Experience with infrastructure automation or configuration management tools.

Familiarity with database performance tuning for large datasets.

Experience supporting GPU-enabled workloads.

Beyond Just Work

As a company in healthcare, we want our people to be happy and healthy, in and out of the office. In addition to competitive pay, we ensure everyone on our team is supported with savings, schedule, and insurance options that promote long-term health and personal growth.

Our office environment is designed for creativity and agility: with walls as notepads and couches for collaboration. We’re located in the heart of Philadelphia, with views of the city so you can spend your time focusing on what matters most.

At Proscia, we don’t just accept differences — we celebrate them, we support them, and we thrive on them for the benefit of our employees, our products, and our community. Proscia is proud to be an equal opportunity workplace.