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Mechanical Engineer III

10xgenomics

Singapore Office (SGP.Singapore (Office)) permanent

Posted: November 21, 2025

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Job Description

About the role:

We are seeking an outstanding Mechanical Engineer II or III to join the Hardware Engineering group to support our ultra-precision mechanical designs and execution of 10x products. The ideal candidate will have a strong background in Mechanical Engineering or Mechatronics in automation and life sciences instrumentation. Demonstrated hands-on experience with SolidWorks and PDM software is required. Previous experience in producing mechanical designs that include automation, fluid handling and instrument structural components are a must.

What you will be doing:

• Proven experience in the design, development, and successful release of precision mechanisms and mechanical assemblies for life science instrumentation or medical capital equipment.

• Designing pneumatic systems for microfluidic management, including pressure control architecture and the selection of sensors, valves and pumps.

• Developing instrument electro-mechanical and structural components

• Coordinate designs with other key functions including Assay, Optical, Electrical and System Engineering.

• Producing mechanical design documentation, in support of releasing new products into manufacturing.

• Collaborate with teams based in the US and globally in the Instrument design and development.

• Work with vendors and suppliers, ensuring quality and reliability in externally sourced components.

To be successful, you will need:

• B.S degree in Mechanical Engineering or Mechatronics with minimum 2 years of experience in life science instrumentation, and/or automation/robotics mechanical design.

• Proficient in SolidWorks, ARENA, EPDM

• Understanding of GD&T and statistical tolerance analysis

• Understands basic thermal dynamics, fluid dynamics, and stress analysis.

• Familiarity with various ideation methodologies and design for manufacturing principles.

• Familiar in Supplier Engagement and support, domestic and off-shore

• Working knowledge of manufacturing techniques, machining, injection molding and consumables for biotech

• Experience in taking new products from concept through design and into manufacturing.

Nice to Have:

• Working knowledge and understanding of pneumatics is a strong plus

• Experience working under ISO 9001 will be a strong plus.

• Experience with Python programming is high desired

About 10x Genomics

At 10x Genomics, accelerating our understanding of biology is more than a mission for us. It is a commitment. This is the century of biology, and the breakthroughs we make now have the potential to change the world.

We enable scientists to advance their research, allowing them to address scientific questions they did not even know they could ask. Our tools have enabled fundamental discoveries across biology including cancer, immunology, and neuroscience.

Our teams are empowered and encouraged to follow their passions, pursue new ideas, and perform at their best in an inclusive and dynamic environment. We know that behind every scientific breakthrough, there is a deep infrastructure of talented people driving the life sciences industry and making it possible for scientists and clinicians to make new strides. We are dedicated to finding the very best person for every aspect of our work because the innovations and discoveries that we enable together will lead to better technologies, better treatments, and a better future. Find out how you can make a 10x difference.

Individuals seeking employment at 10x Genomics are considered without regards to race, color, religion, national origin, age, sex, marital status, ancestry, physical or mental disability, veteran status, gender identity, or sexual orientation, or any other characteristic protected by applicable law.

10x does not accept unsolicited applicants submitted by third-party recruiters or agencies. Any resume or application submitted to 10x without a vendor agreement in place will be considered unsolicited and property of 10x, and 10x will not pay a placement fee.

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