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Associate Director/Director, Strategy & Operations – AI Initiatives

Bridgebio

Palo Alto, California, United States; San Francisco, California, United States (Palo Alto - 3160 Porter, San Francisco - 1800 Owens) Hybrid permanent

Posted: December 9, 2025

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Job Description

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.

Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

What You'll Do

The Associate Director/Director, Strategy & Operations — AI Initiatives will play a critical role in the delivery and adoption of AI-enabled solutions that accelerate how BridgeBio works across R&D, G&A, and Commercial. This high-impact role will scope high-ROI use cases, run rapid prototypes through to scaled deployment, and establish right-sized implementation and governance structures. You will partner cross-functionally to remove bottlenecks, stand up practical copilots and analytics, measure outcomes (cycle-time, quality, cost, compliance), and drive change management so AI becomes a durable advantage for BridgeBio and the patients we serve. The role will report to the Chief of Staff to the CEO with dotted line reporting to the Chief People Officer.

Responsibilities

• Strategic Planning and Execution

• Work with the CEO, Chief of Staff, Chief People Officer, and BridgeBio AI Taskforce to set the company’s strategic vision on AI and identify the highest-impact projects to the business

• Define and run lightweight operating mechanisms (intake/triage, sprint cadences, stage gates, risk reviews, release and enablement plans)

• Program Delivery and Cross-functional Partnership

• Lead end-to-end delivery of high-priority, select AI initiatives: problem framing, rapid prototyping/POC, validation, pilot, and scaled deployment with clear acceptance and success criteria. Collaborate with IT, People Team, and Functional stakeholders

• Remove blockers, manage RAID (risks, assumptions, issues, dependencies), and ensure initiatives land with durable ownership and support

• Stakeholder Communication

• Develop and deliver executive-level materials that synthesize technical and business content into clear, concise, and actionable narratives for leadership, the Board of Directors, and cross-functional teams

• Translate between scientific, clinical, technical, and business stakeholders to drive alignment and decisions; regularly report impact metrics and use feedback loops to surface and communicate lessons learned

• Create playbooks, enablement assets, and job aids that support adoption and change management across functions

• Be an AI evangelist, inspiring and empowering teams across the company to embrace AI as a core enabler of growth and innovation

• External Landscape Mapping and Vendor Strategy

• Maintain a comprehensive view of the AI landscape. Follow thought leaders, blogs, and progress from leading companies in the space

• identify peer companies that are on the leading edge of AI innovation and integrate best practices

• Evaluate platforms and vendors; negotiate scope, timelines, and pricing; align with enterprise architecture and data governance. Make Buy vs. Build recommendations

Where You'll Work

This is a fully in-person role and requires in-office collaboration every day in our San Francisco or Palo Alto Office. Some amount of travel to conferences and vendors will be required.

Who You Are

• Bachelor’s degree in the Life Sciences or Computer Science

• A higher degree or equivalent, such as an M.S., M.B.A., M.D., Ph.D., or related, is preferred

• 3–5+ years of professional experience across strategy & operations, product operations, transformation initiatives, or consulting

• Biopharma industry experience is helpful but is not required

• Proven track record delivering AI/ML or GenAI initiatives from POC to scaled adoption with real business impact

• Deep passion for AI and how it can be applied across the work of a biopharma company to expedite the development of meaningful medicines

• Knowledge of technical developments and industry trends, with a broad network across the biotech and/or tech industries

• Ability to translate between scientific, technical, and business audiences

• Passion for helping patients and accelerating the development of life-changing medicines

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.

Financial Benefits:

• Market leading compensation

• 401K with 100% employer match on first 3% & 50% on the next 2%

• Employee stock purchase program

• Pre-tax commuter benefits

• Referral program with $2,500 award for hired referrals

Health & Wellbeing:

• Comprehensive health care with 100% premiums covered - no cost to you and dependents

• Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)

• Hybrid work model - employees have the autonomy in where and how they do their work

• Unlimited flexible paid time off - take the time that you need

• Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents

• Flex spending accounts & company-provided group term life & disability

• Subsidized lunch via Forkable on days worked from our office

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility

• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching

• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary
$185,000—$275,000 USD

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