Vice President, Drug Discovery

About Us
Crescent Biopharma’s vision is to build a world leading oncology company bringing the next wave of therapies for cancer patients. The Company’s clinical-stage pipeline includes its lead program, a PD-1 x VEGF bispecific antibody, as well as novel antibody-drug conjugates. By leveraging multiple modalities and established targets, Crescent aims to rapidly advance potentially transformative therapies either as single agents or as part of combination regimens to treat a range of solid tumors. For more information, visit www.crescentbiopharma.com and follow the Company on LinkedIn and X.

Position Overview
Crescent Biopharma is seeking a Vice President, Drug Discovery to provide strategic and technical oversight for all aspects of Crescent’s novel drug discovery efforts from lead identification to preclinical development and commercialization. The ideal candidate is a creative and innovative scientist who has had senior level scientific/technical responsibility with substantial experience leading the successful discovery and development of drug candidates across many biologics modalities, such as monoclonal antibodies, antibody drug conjugates, and peptides in the fields of immunology and oncology.

Responsibilities:
• Guide the strategic approach for target selection, antibody discovery and therapeutic approach to identify and develop novel drug candidates.
• Build, lead and develop high performing research & preclinical teams.
• Lead technological innovations to drive continual improvements and optimization of Crescent's antibody and ADC programs enabling continued success as the organization grows.
• Effectively manage a departmental budget and deliver results based on work conducted at CROs and external partners.
• Represent the company at scientific conferences and author high impact peer reviewed publications.
• Responsible for delivery of research and development reports to support regulatory submissions (IND/IMPD, information requests, amendments, briefing books, BLA/MAA etc.)

Education & Experience :
• Ph.D. in Life Sciences with a minimum of15 years of combined R&D experience in the biotech/biopharmaceutical industry and world-class academic institutions. M.S. with equivalent experience will also be considered.
• Demonstrated career growth and experience gained in leading growing R&D organizations.
• Deep experience in drug discovery and development in oncology.
• Successful leadership of antibody and ADC program(s) from discovery to preclinical development and commercialization.
• Recognized leader and expert with a track record in cancer research, immunology and cell biology fields.
• Inspires teams by being intellectually and scientifically curious, is extremely scientifically rigorous and creative and creates an environment where imaginative and constructive dialog can flourish, conflict is well-managed and complex issues are driven to full resolution.
• Demonstrated success in attracting world-class scientific talent.
• Hands on experience with regulatory requirements for the development and approval of novel therapeutics in oncology.

What We Offer :
• Opportunity to join a mission-driven team where you'll contribute to impactful work, take on varied responsibilities, and grow quickly in a dynamic environment.
• Competitive compensation, including base salary, performance bonus, and equity.
• 100% employer-paid benefits package.
• Flexible PTO.
• Two, one-week company-wide shutdowns each year.
• A commitment to your professional development, with access to resources, mentorship, and growth opportunities.

The anticipated base pay range for this position is :
$324,000 to $358,000 USD.
Additional Description for Pay Transparency:
Subject to the terms of their respective plans, employees and/or eligible dependents are eligible to participate in the following Company sponsored employee benefit programs: medical, dental, vision, life insurance, short- and long-term disability. Subject to the terms of their respective plans, employees are eligible to participate in the Company’s savings plan (401(k)). This position is eligible to participate in the Company’s long-term incentive program. Subject to the terms of their respective policies and date of hire, Employees are eligible for the following time off benefits: Vacation – Unlimited PTO; Sick time – 10 days per calendar year; Holiday pay, including two Company shut downs; Parental Leave – 16 weeks within one year of the birth/adoption/foster care of a child; FMLA; Military Leave. Additional information can be found through the link below. https://www.crescentbiopharma.com/careers/#benefits

E-Verify:
Crescent Biopharma, Inc. uses E-Verify to confirm the identity and employment eligibility of all new hires.

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Crescent Biopharma is an Equal Opportunity Employer. We are committed to fostering a diverse, inclusive, and equitable workplace where all individuals are valued and respected. Employment decisions are based on qualifications, merit, and business needs, without regard to race, color, religion, gender, sexual orientation, national origin, disability, veteran status, or any other protected status.
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Crescent Biopharma is an Equal Opportunity Employer. We are committed to fostering a diverse, inclusive, and equitable workplace where all individuals are valued and respected. Employment decisions are based on qualifications, merit, and business needs, without regard to race, color, religion, gender, sexual orientation, national origin, disability, veteran status, or any other protected status.