US Senior Medical Director – Early Assets, Immunology

Are you ready to turn ideas into life-changing medicines? At AstraZeneca, we are committed to addressing the unmet needs of patients worldwide through scientific innovation. As a Senior Medical Director, Immunology Early Assets, you will play a crucial role in leveraging our scientific capabilities to positively impact patients' lives. Reporting directly to the US Medical Head, Immunology, you will lead the development of ambitious US medical strategies for our early pipeline of immunology products, including cell therapies. This is an opportunity to seize, design, and influence across a complex matrix system to ensure US needs are integrated into global development plans. Accountabilities: As a strategic leader, you will shape the scientific and medical direction for novel therapies (e.g. cell therapies ), ensuring alignment with pipeline priorities and business objectives - while supporting efforts on lifecycle management of current in-line assets . You will serve as the internal medical expert for emerging assets, collaborating cross-functionally with global teams and external pa rtners. You will partner with global medical and R&D to ensure robust translational and early clinical development plans, incorporating medical insights and real-world data opportunities. Yo ur role will involve crafting compelling scientific narratives, developing solutions for outstanding product launches, and optimizing evidence activities to support practice change initiatives. You will also ensure comprehensive external engagement plans and play an integral role in medical advisory boards. Essential Skills/Experience: Doctoral level degree: MD, PhD, or PharmD 5+ years of experience in the pharmaceutical industry (medical, marketing, R&D, market access roles), or working in a relevant health system setting (clinical, pharmacy, pathway design etc.) Deep medical, clinical or scientific expertise in immunology and/or cell therapy Experienced business leader able to deliver results in a complex matrix environment US regulatory strategy knowledge including product approval, label requirements/negotiation Proven ability to build internal/external networks and to collaborate internally/externally Substantial evidence generation/data expertise, e.g. clinical trial experience (conducted Ph2, Ph3 or Ph4 studies), and/or substantial RWE experience Desirable Skills/Experience: Global and/or R&D experience, or proven track record of supporting early asset or first-in-class product development Relevant experience beyond medical affairs (e.g. in a marketing/R&D/market access role) When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. AstraZeneca offers an environment where you can thrive on energy and pace while making a significant impact on patients' lives. Our commitment to innovation and experimentation empowers our teams to think big and act fast. With countless opportunities for growth and development, you'll be part of a journey that shapes the future of BioPharmaceuticals and contributes to bending the global mortality curve. Ready to make a difference? Apply now and join us on this exciting journey! Date Posted 09-Jan-2026 Closing Date 10-Jan-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.