US HEVA Dupixent Team Lead

Job Title: US HEVA Dupixent Team Lead

Location: Cambridge, MA / Morristown, NJ

About the job

Join the team transforming care for people with immune challenges, rare diseases, cancers, and neurological conditions. In Specialty Care, you’ll help deliver breakthrough treatments that bring hope to patients with some of the highest unmet needs. 

Sanofi's Purpose and Mission:

Sanofi is an R&D-driven, AI-powered biopharma company committed to improving people's lives and delivering compelling growth. We apply our deep understanding of the immune system to invent medicines and vaccines that treat and protect millions of people around the world, with an innovative pipeline that could benefit millions more. Our team is guided by one purpose: we chase the miracles of science to improve people's lives; this inspires us to drive progress and deliver positive impact for our people and the communities we serve, by addressing the most urgent healthcare, environmental, and societal challenges of our time.

Dupixent Purpose:

Dupixent is a significant portfolio for Sanofi. Designed to target underlying drivers of chronic inflammatory disease, Dupixent has received regulatory approvals in more than 60 countries across multiple indications, including atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, prurigo nodularis, chronic spontaneous urticaria, chronic obstructive pulmonary disease, and bullous pemphigoid, spanning diverse age populations. More than one million patients are currently treated with Dupixent globally.

Supported by an extensive clinical development program of more than 60 studies in over 10,000 patients, Sanofi and Regeneron are studying dupilumab in a broad range of diseases driven by type 2 inflammation or other allergic processes in phase 3 studies. As the portfolio continues to expand, Dupixent is redefining standards of care, broadening patient impact, and delivering sustained value across healthcare systems worldwide.

HEVA Vision, Mission, and Values:

We are one bold HEOR team leveraging innovative HEOR to transform patient care and access.  As HEOR experts, we lead the generation and dissemination of robust, business-relevant evidence to demonstrate value and drive access to medicines. The HEVA organization is driven by five core values that define how we work and deliver impact. We operate as One Team, partnering without boundaries while pursuing a Bold Purpose through ambitious, measurable goals. Grounded in Scientific Excellence with Relevance and deep technical expertise, we embrace Innovation in Action to transform how we research and deliver Impact for People, creating meaningful outcomes for patients, the healthcare ecosystem, and our colleagues who make it all possible.

About Sanofi

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives. 

Main responsibilities:

This role leads US HEVA strategy and execution for Dupixent across indications, leading a team in ensuring the generation, translation, and dissemination of high-quality, decision-relevant evidence to impact access in the United States.

• Strategic Business Impact

• Drive measurable business impact through strategic US HEVA initiatives that directly support US commercial objectives and US market access goals compliantly and efficiently

• Develop and execute comprehensive US HEVA strategies that maximize product value propositions and competitive positioning, ensuring alignment with Global HEVA strategy

• Partner with commercial teams to translate HEVA insights into actionable business strategies

• Drive development of business-relevant US research agendas and strategies through cross-functional input and alignment

• Leadership and Team Management

• Provide exceptional leadership to the US Dupixent HEVA team, fostering a culture of excellence, innovation, and impact driven performance

• Mentor and develop team members to build world-class HEVA capabilities within the organization

• Drive organizational change and process improvements to enhance team effectiveness and business impact

• Represent HEVA with the US Dupixent Franchise Leadership Team

• Internal Partnerships and Senior Management Engagement

• Build and maintain strong relationships with the cross functional teams to ensure pricing and access decisions and brand strategies are supported with demonstratable value of assets per robust evidence packages including real world evidence

• Align closely with the Global HEVA team to ensure inclusion of US insights into global strategic plans and coordinate evidence generation, modelling, and evidence synthesis activities

• Deliver compelling presentations to senior leadership, including C-suite executives and US leadership teams

• Communicate complex health economics concepts and strategic recommendations to senior stakeholders with clarity and impact

• Influence key business decisions through data-driven insights and strategic HEVA recommendations

• Ensure clinical development plans are designed to deliver true differentiation aligned to Sanofi Dupixent portfolio ambitions

• Health Economics Research and Evidence Generation

• Oversee the design, execution, publication, and further dissemination of high-quality health economics and outcomes research studies to ensure the highest quality of evidence is delivered to support business objectives

• Develop comprehensive real-world evidence strategies that support product lifecycle management

• Ensure scientific rigor and regulatory compliance across all HEVA research activities

• Manage the development of US launch strategies and evidence generation plans, providing strategic HEVA input into Integrated Evidence Generation Plans (IEGPs) to ensure alignment across clinical, real-world evidence, and value demonstration objectives

• Across the US HEVA Dupixent team, compliantly lead efforts to further HEOR dissemination, application, and proactive and/or promotional use with US stakeholders (eg, HCEI, PIE, consistent with FDA label)

• Partner with Access Strategy teams and US Market Access teams to execute on innovative payer partnership health economics and outcomes research studies and analytics aligned with franchise priorities

• Stakeholder Engagement and External Partnerships

• Build and maintain strategic relationships with key external stakeholders, including payers, health technology assessment bodies, and academic institutions

• Represent Sanofi at major scientific conferences and industry forums

• Collaborate with external research partners and key opinion leaders to advance HEVA science

• Support external engagement with key external evidence bodies (eg, ICER, PDAB, IRA) on related pricing and access challenges, and evolving reimbursement frameworks 

• As a leader in Sanofi’s HEVA organization, seek opportunities to actively participate and engage with external professional HEOR societies

About you

This is a senior leadership position requiring exceptional capabilities and a proven track record of delivering transformational business impact through strategic HEVA excellence. The successful candidate will play a critical role in advancing Sanofi's US Dupixent franchise and driving sustainable competitive advantage through world-class health economics and value assessment capabilities.

• Minimum 10 years of experience in health economics, outcomes research, or a related field

• Advanced degree (PhD, PharmD, Masters or equivalent) in health economics, epidemiology, public health, economics, or related field required

• Demonstrated expertise in health economic modeling, real-world evidence generation, and outcomes research methodologies

• Deep expertise in US healthcare, payer dynamics, and policy, with a track record of translating evidence into strategic impact 

• Proven track record of successful market access and reimbursement support through HEVA evidence and ability to influence decision-making at the highest levels of the organization using HEVA developed insights and evidence

• Strong command of US evidence dissemination (HCEI/PIE, reactive/proactive, CFL, AMCP dossiers) 

• Exceptional leadership skills with demonstrated ability to inspire, motivate, and develop high-performing teams

• Strong change management capabilities and experience leading organizational transformation initiatives

• Proven ability to influence and collaborate effectively across all organizational levels and functions

• Extensive experience in immunology therapeutic areas required, including deep understanding of disease pathophysiology, treatment paradigms, and market dynamics

• Strong written and verbal communication skills in English

• Ability to synthesize complex data into clear, actionable insights and strategic recommendations

• 20% travel domestic and international

Why Choose Us?  

• Bring the miracles of science to life alongside a supportive, future-focused team. 

• Discover endless opportunities to grow your talent and drive your career, whether it’s through a promotion or lateral move, at home or internationally. 

• Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact. 

• Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks’ gender-neutral parental leave.

Sanofi Inc. and its U.S. affiliates are Equal Opportunity employers committed to a culturally inclusive workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. 

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Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

US and Puerto Rico Residents Only

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

North America Applicants Only

The salary range for this position is:

$232,500.00 - $335,833.33

All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK.