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Thesis Work, 30 Credits - Mesoporous materials platform for poorly soluble drug substances

AstraZeneca

Sweden - Gothenburg permanent

Posted: March 24, 2026

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Quick Summary

Join us to advance tablet formulation for poorly soluble drugs

Job Description

Are you interested in solving key formulation challenges for poorly soluble drugs? We offer a thesis opportunity to evaluate mesoporous materials as platforms for drug amorphisation, using techniques like PXRD and dissolution studies. Join us to advance tablet formulation and contribute to innovative drug delivery solutions! 

About AstraZeneca:  

AstraZeneca is a global, science-led, patient-centered biopharmaceutical company focusing on discovering, developing, and commercializing prescription medicines for some of the world’s most serious diseases. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we're dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.   

About the Opportunity:  

As a Thesis Worker at AstraZeneca, you’ll find an environment that’s full of unique opportunities and exciting challenges. Here, you’ll have the opportunity to pursue your areas of interest whilst equally developing a broad skillset and knowledge base to get the best out of your experience. You’ll be working on meaningful projects to make an impact and deliver real value for our patients and our business.  

Thesis work description:   

Poor aqueous solubility is a common challenge for new drug candidates, impacting their development and performance. Mesoporous materials, such as mesoporous silica, show promise in enhancing drug amorphisation and improving dissolution due to their high surface area and nanometre-scale pore structure. This thesis project aims to evaluate the effectiveness of different mesoporous materials for poorly soluble drugs and investigate drug loading limitations relative to solubility in organic solvents. 

Key Objectives: 

• Assess a variety of mesoporous materials as platforms for poorly soluble drug substances. 
• Determine drug loading limitations in relation to solubility in organic solvents. 
• Characterize the solid-state properties of loaded mesoporous particles using PXRD and other solid-state methods. 
• Formulate loaded mesoporous particles into tablets and evaluate their dissolution behavior using a dissolution apparatus. 
• Generate practical insights supporting the use of mesoporous materials in drug development. 

Placement: 

This is an on-site position at AstraZeneca Gothenburg. AstraZeneca does not support with accommodations for this role.  

Structure:  

Duration: Fall term 2026  

Credits: 30  

  

Essential Requirements:  

• Enrolled in a Master's program within Pharmacy, Process Engineering 
• Excellent English communication skills, including speaking, presenting and scientific writing. 

So, what’s next?   

Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can't wait to hear from you!   

We welcome your application as soon as possible, but ahead of the scheduled closing date 15th of April 2026. In the event that we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.   

Date Posted

24-Mar-2026

Closing Date

15-Apr-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.

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