Summer Intern, Process Analytical Technology

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Process Analytical Technology (PAT) Intern will support Arrowhead Pharmaceuticals’ advancement toward automated and continuous manufacturing by contributing to the development and optimization of analytical technologies used to monitor product manufacturing. This internship offers hands-on experience working with PAT scientists and Innovation Engineers to generate and analyze real-time manufacturing data. The intern will gain exposure to analytical instrumentation, data modeling, and advanced manufacturing concepts that support both current and future production platforms.

This is an 11-week Summer Internship Program paying $21.00 per hour and requires full-time, onsite work five days per week at the designated location.

Responsibilities

• Assist in the development and optimization of online, at-line, and in-line analytical technologies used to monitor, analyze, and control manufacturing processes.

• Utilize analytical instrumentation such as IR, UV, and NMR to generate PAT data supporting product and process understanding.

• Support data analysis and model development using PAT-generated data.

• Collaborate on the design, implementation, and validation of new analytical technologies in a manufacturing environment.

• Perform routine analytical testing independently in support of new and ongoing projects.

• Document experimental results and findings to support method development and validation activities.

• Work closely with PAT scientists, Innovation Engineers, and cross-functional manufacturing teams.

Requirements

• Currently enrolled student at an accredited university or college, majoring in Chemistry or a related scientific discipline.

• Understanding of analytical chemistry principles and instrumentation.

• Excellent verbal and written communication skills.

• Demonstrated innovation, creativity, and resilience in problem-solving.

• Ability to work independently on assigned tasks.

• Flexibility to adapt to changing priorities in a dynamic environment.

• Proficiency in Microsoft Office applications.

Preferred

• Skills and knowledge in handling, analyzing, and characterizing chemicals.

• Experience with statistical data analysis.

• Programming, modeling, or automation experience.

• Interest in continuous manufacturing, process analytics, or advanced manufacturing technologies.

• Prior laboratory or analytical research experience.

Wisconsin pay range
$9,240—$9,240 USD

Arrowhead provides competitive salaries and an excellent benefit package.

All applicants must have authorization to work in the US for a company.

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