Staff Software Engineer (Commercial) #4508

Our mission is to detect cancer early, when it can be cured. We are working to change the trajectory of cancer mortality and bring stakeholders together to adopt innovative, safe, and effective technologies that can transform cancer care.

We are a healthcare company, pioneering new technologies to advance early cancer detection. We have built a multi-disciplinary organization of scientists, engineers, and physicians and we are using the power of next-generation sequencing (NGS), population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine’s greatest challenges.

GRAIL is headquartered in the bay area of California, with locations in Washington, D.C., North Carolina, and the United Kingdom. It is supported by leading global investors and pharmaceutical, technology, and healthcare companies.

For more information, please visit grail.com

GRAIL is seeking a Staff Software Engineer (L7) to join the Commercial Engineering team responsible for patient- and provider-facing applications that power our core product—the Galleri® test. This role directly supports my.grail.com and provider.grail.com, the digital front doors used by patients and healthcare professionals to access test results and care coordination tools.
You will help scale systems that are mission-critical, security-sensitive, and deeply integrated with GRAIL’s clinical infrastructure. You’ll partner with engineers, product managers, clinicians, and designers to deliver software that improves how we detect cancer early.

This role is based in Menlo Park, California, and will move to Sunnyvale, California in Fall 2026. It offers a flexible work arrangement, with the ability to work from GRAIL's office or from home. Our current flexible work arrangement policy requires that a minimum of 60%, or 24 hours, of your total work week be on-site. Your specific schedule, determined in collaboration with your manager, will align with team and business needs and could exceed the 40% requirement for the site. At our Menlo Park campus, Tuesdays and Thursdays are the key days where we encourage on-site presence to engage in events and on-site activities.

Responsibilities:
• Lead the design and development of secure, cloud-native backend systems and user-facing applications used by patients and clinicians
• Build distributed microservices using Go, integrate with AWS infrastructure, and ensure system reliability and scalability
• Develop robust UIs using React, collaborating closely with designers and product managers
• Contribute to system architecture and propose improvements in observability, reliability, and performance
• Serve as a technical leader across cross-functional projects with moderate to high complexity
• Collaborate with product and business teams to define roadmap priorities and translate requirements into execution plans
• Mentor and support engineers through code reviews, pair programming, and technical design discussions
• Provide guidance on engineering best practices, tools, and testing strategies
• Communicate project risks, trade-offs, and progress clearly with engineering leadership and stakeholders
These responsibilities summarize the role’s primary responsibilities and are not an exhaustive list. They may change at the company’s discretion.

Required Qualifications:
• Bachelor’s or Master’s degree in Computer Science, Engineering, or equivalent experience
• 8+ years of professional experience developing backend and full-stack applications in production
• Strong experience with Go and/or Java, and at least one modern frontend framework (React, Angular, or equivalent)
• Hands-on experience building and scaling microservice architectures in AWS, GCP, or Azure
• Experience with Kubernetes, Docker, and event-driven systems (Kafka, RabbitMQ, or equivalent)
• Experience working in Agile environments with modern CI/CD pipelines and testing frameworks
• Strong understanding of security, privacy, and compliance considerations—especially when handling regulated data
• Demonstrated ability to lead and execute cross-functional engineering initiatives

Preferred Qualifications:
• Experience with Go in a cloud-based, production environment
• Experience developing customer-facing applications in healthcare, life sciences, or another regulated industry
• Familiarity with HIPAA, clinical workflows, or EHR integration
• Hands-on experience with gRPC, Terraform, or Infrastructure as Code (IaC)
• Experience building tools with React, Redux/Context API, and component-based design systems
• Exposure to FHIR, HL7, or other clinical data interoperability standards
• Experience mentoring engineers or leading a team through a full product lifecycle
• Demonstrated ability to identify and resolve ambiguous, multi-stakeholder technical problems

The expected, full-time, annual base pay scale for this position is $169k $253k. Actual base pay will consider skills, experience, and location.

This role may be eligible for other forms of compensation, including an annual bonus and/or incentives, subject to the terms of the applicable plans and Company discretion. This range reflects a good-faith estimate of the range that the Company reasonably expects to pay for the position upon hire; the actual compensation offered may vary depending on factors such as the candidate’s qualifications. Employees in this role are also eligible for GRAIL’s comprehensive and competitive benefits package, offered in accordance with our applicable plans and policies. This package currently includes flexible time-off or vacation; a 401(k) retirement plan with employer match; medical, dental, and vision coverage; and carefully selected mindfulness programs.

GRAIL is an equal employment opportunity employer, and we are committed to building a workplace where every individual can thrive, contribute, and grow. All qualified applicants will receive consideration for employment without regard to race, color, religion, national origin, sex, gender, gender identity, sexual orientation, age, disability, status as a protected veteran, , or any other class or characteristic protected by applicable federal, state, and local laws. Additionally, GRAIL will consider for employment qualified applicants with arrest and conviction records in a manner consistent with applicable law and provide reasonable accommodations to qualified individuals with disabilities. Please contact us at [email protected] if you require an accommodation to apply for an open position.

GRAIL maintains a drug-free workplace. We welcome job-seekers from all backgrounds to join us!