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Staff Project Manager and Scrum Master

Twistbioscience

USA - South San Francisco, CA Hybrid permanent

Posted: December 2, 2025

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Job Description

Staff Project Manager and Scrum Master (Hybrid in South San Francisco, CA)

Job Description:

At Twist Bioscience, we help our customers change the world for the better. Our DNA-based tools are enabling researchers across a variety of scientific disciplines to achieve groundbreaking discoveries. We continue to drive biological innovations aimed at making the world safer, healthier, and more sustainable.

We are seeking an experienced Staff Project Manager and Scrum Master to join our team. The ideal candidate will have a proven track record in managing a range of complex, high-impact projects with strong organizational leadership and influencing skills. As a Staff Project Manager and Scrum Master, you will work closely with stakeholders, both business and software engineering, and play a crucial role in coaching and guiding the Scrum team(s) to enable meeting the goals of the organization.

Key Responsibilities:

• Lead the project team in using Agile methodology and scrum practices, or a hybrid practice to fit the team needs

• Collaborates with cross functional team members to develop detailed project plans, and coordinates activities across multiple functional groups including PMO, R&D, tech transfer, manufacturing, and QC/QA.

• Provides strategic guidance to cross-functional teams, and while managing multiple projects in parallel.

• Organize sprints, daily stand-ups, and retrospective meetings, and additional meetings to assist the project teams

• Assist with coordinating user story grooming, sprint planning and review, and software demos

• Work with the team to proactively remove impediments and ensure project is on track

• Measure project performance and assist with project risk management

• Report project status, risks, and escalations

• Work with product owners to help manage backlogs and new project requests

Qualifications:

• Bachelor’s degree in a life science, engineering, or associated scientific field

• 8+ years of combined Scrum Master and Project Management experience

• 3+ years of experience managing projects in biotech, medical device or pharmaceutical industry, with prior technical experience.

• Scrum Master certification

• Business or systems analysis experience

• Solid SDLC experience background, with familiarity of cloud and web technologies

• Ability to work in a fast paced, agile development environment

• Strong organizational and multitasking abilities

• Excellent written and verbal communication skills

Preferred Qualifications

• Passion for improving the accessibility and usability of scientific products through digital innovation.

• Experience working with geographically dispersed software development teams

• Familiarity with both product development and manufacturing activities

• Familiarity with lab management systems such as LIMs

• Experience working within) controlled or regulated environments (e.g., ISO 13485, CLIA, etc.), with involvement in documentation, validation planning, or audit preparation

• Familiarity with eCommerce platforms and Business Applications such as Salesforce.com and SAP

• Familiarity with development and code management systems like Jira and GitHub.

• Experience in working in a scientific or biotech environment

• PMP certification

About Twist Bioscience

Twist Bioscience synthesizes genes from scratch, known as “writing” DNA. Just as children learn to both read and write, the next phase of development for the genomics revolution is the ability to write DNA.

At Twist Bioscience, we work in service of people who are changing the world for the better. In fields such as health care, agriculture, industrial chemicals and data storage, our unique silicon-based DNA Synthesis Platform provides precision at a scale that is otherwise unavailable to our customers.

Twist Bioscience Corporation is an Equal Opportunity Employer. Twist Bioscience Corporation provides equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, genetic characteristics, or any other category protected by law.

The base cash compensation for this California-based role is below. In addition to base salary, this role is eligible for bonus, equity, and a generous benefits package. Final compensation amounts are determined by multiple factors, including candidate skill, experience, expertise, and location and may vary from the amount listed above. Compensation may be different in other locations.
San Francisco Bay Area Pay Range
$165,475—$225,657 USD

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