Staff Applied AI Engineer

We Breathe Life Into Data

At Komodo Health, our mission is to reduce the global burden of disease. And we believe that smarter use of data is essential to this mission. That’s why we built the Healthcare Map — the industry’s largest, most complete, precise view of the U.S. healthcare system — by combining de-identified, real-world patient data with innovative algorithms and decades of clinical experience. The Healthcare Map serves as our foundation for a powerful suite of software applications, helping us answer healthcare’s most complex questions for our partners. Across the healthcare ecosystem, we’re helping our clients unlock critical insights to track detailed patient behaviors and treatment patterns, identify gaps in care, address unmet patient needs, and reduce the global burden of disease.

As we pursue these goals, it remains essential to us that we stay grounded in our values: be awesome, seek growth, deliver “wow,” and enjoy the ride. At Komodo, you will be joining a team of ambitious, supportive Dragons with diverse backgrounds but a shared passion to deliver on our mission to reduce the burden of disease — and enjoy the journey along the way.

The Opportunity at Komodo Health:

Healthcare in the U.S. is a mess. Komodo Health is fixing that—with data. We’ve mapped the patient journey across the country to build the most complete picture of disease burden and treatment gaps. Our customers—pharma companies, payers, and health systems—use this data to make decisions that meaningfully improve patient outcomes.

Labs@Komodo builds the AI-native platforms and systems that turn this data into action. We are the team behind Marmot, Komodo’s AI-native product—designed with AI embedded directly into both the interface and the development workflow. By combining Komodo’s unmatched healthcare data with modern LLMs, Marmot is delivering some of the most compelling real-world insights of the new AI era.

Mission of the Role:

As a Staff Applied AI Engineer, you are a cross-functional AI leader and strategic thought partner. This role exists to define Komodo’s long-term AI capabilities, set company-wide technical standards, architect foundational AI systems, and guide teams toward scalable, safe, and innovative AI development. You will influence data strategy, drive build-vs-buy evaluations, and meaningfully shift Komodo’s AI-native infrastructure and culture.

Looking back on your first 12 months at Komodo Health, you will have accomplished…

• Defined strategic AI capabilities aligned to Komodo’s core business and product roadmap.

• Architected reusable AI platforms, frameworks, or orchestration layers adopted across multiple teams.

• Set standards for responsible AI, safety, prompt design, explainability, and bias mitigation.

• Led high-impact AI initiatives that shaped Komodo’s internal and external product strategy.

• Provided deep technical guidance that unblocked complex problems across teams.

• Built internal alignment on AI investment strategy, tooling, governance, and long-term direction.

What you’ll own:

• Help design company-wide AI vision, standards, and reference architectures.

• Defining and building foundational AI platforms (e.g., internal agent frameworks, orchestration systems).

• Acting as a multiplier by mentoring teams, running workshops, and driving organizational knowledge sharing.

• Making high-level technical decisions, including evaluating major build-vs-buy choices for platforms and tooling.

• Shaping Komodo’s data strategy from an AI perspective—requirements, quality, orientation, and long-term structure.

• Leading complex applied research initiatives that push Komodo into new AI capability frontiers.

• Ensuring Komodo’s AI systems meet high bars for reliability, accountability, ethics, and transparency.

What you bring to Komodo Health (required):

• Recognized expert in applied AI with demonstrated impact across multiple teams or organizational domains.

• Extensive experience architecting end-to-end AI systems, multi-agent architectures, and large-scale orchestration frameworks.

• Deep technical sophistication with LLMs, agent safety, responsible AI, observability, and ML lifecycle governance.

• Strong fluency in Python, GenAI frameworks (vLLM, Strands, Crew AI), and full-stack system integration.

• Experience influencing strategic technical direction and driving adoption of foundational AI frameworks.

• Exceptional communication skills with the ability to align diverse stakeholders.

Expectations of AI Use in this role (required):

You will operate as a strategic AI leader—setting patterns, driving adoption, and ensuring Komodo stays at the forefront of applied AI innovation.

Additional skills and experience we’d prioritize (nice to have)…

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Deep healthcare data or healthcare system expertise

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Experience leading large-scale distributed data and compute systems (e.g., Spark, Databricks, Snowflake).

** Location flexible to NYC or SF hybrid, and remote

The pay range for each job posting reflects a minimum and maximum range of annual base pay that we reasonably expect to pay for this position within the US. We carefully consider multiple business-related factors when determining compensation, including job-related skills, work experience, geographic work location, relevant training and certifications, business needs and market demands.

The starting annual base pay for this role is listed below. This position may be eligible for performance-based bonuses as determined in the Company’s sole discretion and in accordance with a written agreement or plan. This role may also be eligible for equity awards. In addition, this role is eligible for benefits including, but not limited to, comprehensive health, dental, and vision insurance; flexible time off and holidays; 401(k) with company match; disability insurance and life insurance; and leaves of absence in accordance with applicable state and local laws and regulations and company policy.

San Francisco Bay Area and New York City:
$274,000—$322,000 USD

All Other US Locations:
$238,000—$280,000 USD

Komodo's AI Standard

At Komodo, we're not just witnessing the AI revolution – we're leading it. This is a pivotal moment in time, where being first to market with AI transforms industries and sets the bar. We've already established industry leadership in leveraging AI to revolutionize healthcare, and we expect every team member to contribute. AI here isn't optional; it's foundational. We expect you to integrate AI into your daily work – from summarizing documents to automating workflows and uncovering insights. This isn't just about efficiency; it's about making every moment more meaningful, building on trust in AI, and driving our collective success.

Join us in shaping the future of healthcare intelligence.

Where You’ll Work

Komodo Health has a hybrid work model with hubs in San Francisco, New York City, and Chicago. Roles vary — some can be performed from anywhere in the country, others are scoped to a specific region, and some are based near one of our hubs. For hub-based Dragons, we're building intentional in-office rhythms alongside the flexibility that's core to how we work. Whatever your setup, expectations will always be clear before you join.

Equal Opportunity Statement

Komodo Health provides equal employment opportunities to all applicants and employees. We prohibit discrimination and harassment of any type with regard to race, color, religion, age, sex, national origin, disability status, genetics, protected veteran status, sexual orientation, gender identity or expression, or any other characteristic protected by federal, state, or local laws.

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