Sr. Director, Evidence Generation

Mavericks Wanted

When was the last time you achieved the impossible? If that thought feels overwhelming, you might want to pause here, but if it sparks excitement...read on

In 2015, we pioneered a “moneyball for biotech” approach, pooling projects and promising early-stage research from academia together under one financial umbrella to reduce risk and unleash innovation. This model allows science and small teams of experts to lead the way. We build bridges to groundbreaking advancements in rare disease, and develop life-changing medicines for patients with unmet needs as fast as humanly possible.

Together we define white space, push boundaries and empower people to solve problems. If you're someone who defies convention, join us and work alongside some of the most respected minds in the industry. Together, we'll ask "why not?" and help reengineer the future of biopharma.

Affiliate Overview

Eidos Therapeutics, an affiliate within BridgeBio Pharma, is a commercial-stage biopharmaceutical company focused on Transthyretin Amyloid Cardiomyopathy (ATTR-CM).

What You'll Do

• The Evidence Generation team within Medical Affairs is dedicated to developing high-quality, real-world, and comparative evidence that informs clinical decision-making, demonstrates the value of our therapies, and advances patient outcomes. This role centers on comparative effectiveness research (CER) and health outcomes innovation, with a secondary focus on advanced analytics to optimize evidence strategies

• The successful candidate will design, execute, and communicate evidence generation initiatives that support product value, differentiation, and access across the lifecycle—the immediate need of post-launch real-world studies

Responsibilities

Comparative Effectiveness & Outcomes Research

• Lead and design comparative effectiveness and health outcomes studies using real-world data (RWD), registries, claims databases, and clinical data sources

• Develop strategic evidence plans that address clinical, payer, and patient stakeholder needs

• Apply advanced study designs (e.g., propensity score matching, instrumental variables, target trial emulation) to generate credible, high-impact insights

• Collaborate cross-functionally with Clinical Development, Health Economics and Outcomes Research (HEOR), Market Access, and Data Science teams to align evidence strategies with organizational priorities

• Communicate findings in scientific forums, peer-reviewed publications, and internal stakeholder briefings

Scientific Leadership & Collaboration

• Serve as a subject matter expert in comparative effectiveness research within Medical Affairs

• Represent the company in external collaborations, advisory boards, and industry working groups focused on RWE and methodological innovation

• Provide mentorship and scientific guidance to evidence scientists and cross-functional partners

Where You'll Work

• This a U.S-based remote role that will require quarterly, or as needed visits to our San Francisco, CA office.

Who You Are

• Advanced degree (PhD, PharmD, MD, MPH, or MS) in Epidemiology, Health Economics, Biostatistics, Data Science, or related field

• 5–10+ years of experience in evidence generation, comparative effectiveness, or HEOR in a pharmaceutical, biotech, or academic setting

• Demonstrated expertise in designing and executing RWD studies and comparative analyses

• Strong track record of scientific publications and presentations

• Excellent communication, strategic thinking, and stakeholder management skills

Preferred Attributes

• Preferred experience in comparative effectiveness and statistical methodology

• Ability to bridge technical analytical methods and clinical impact narratives

Rewarding Those Who Make the Mission Possible

We have high expectations for our team members. We make sure those working hard for patients are rewarded and cared for in return.

Financial Benefits:

• Market leading compensation

• 401K with 100% employer match on first 3% & 50% on the next 2%

• Employee stock purchase program

• Pre-tax commuter benefits

• Referral program with $2,500 award for hired referrals

Health & Wellbeing:

• Comprehensive health care with 100% premiums covered - no cost to you and dependents

• Mental health support via Spring Health (6 therapy sessions & 6 coaching sessions)

• Hybrid work model - employees have the autonomy in where and how they do their work

• Unlimited flexible paid time off - take the time that you need

• Paid parental leave - 4 months for birthing parents & 2 months for non-birthing parents

• Flex spending accounts & company-provided group term life & disability

• Subsidized lunch via Forkable on days worked from our office

Skill Development & Career Paths:

• People are part of our growth and success story - from discovery to active drug trials and FDA pipelines, there are endless opportunities for skill development and internal mobility

• We provide career pathing through regular feedback, continuous education and professional development programs via LinkedIn Learning, LifeLabs, Spring Health & BetterUp Coaching

• We celebrate strong performance with financial rewards, peer-to-peer recognition, and growth opportunities

At BridgeBio, we strive to provide a market-competitive total rewards package, including base pay, an annual performance bonus, company equity, and generous health benefits. Below is the anticipated salary range for candidates for this role who will work in California. The final salary offered to a successful candidate will depend on several factors that may include but are not limited to the type and length of experience within the job, type, and length of experience within the industry, educational background, location of residence and performance during the interview process. BridgeBio is a multi-state employer, and this salary range may not reflect positions based in other states.

Salary
$265,000—$345,000 USD