Sr. Director, Commercial Strategy Lead

Alkeus Pharmaceuticals, Inc. is a clinical-stage biotech company focused on the development of innovative therapies to treat serious diseases of the eye with high unmet need. Based in Cambridge, Mass., Alkeus was founded in 2010, and since that time has been developing its lead compound, gildeuretinol acetate (ALK-001). Designated as a breakthrough therapy and granted orphan drug status by the U.S. Food and Drug Administration, gildeuretinol is being evaluated in multiple clinical trials for the treatment of Stargardt disease and geographic atrophy (GA) secondary to age-related macular degeneration (AMD), a leading cause of blindness in the U.S.

Position Summary:

The Senior Director, Commercial Strategy lead is responsible for understanding the evolving needs of the Stargardt community and shaping the brand strategy, including the execution of comprehensive marketing plans. This role will lead brand planning, product launches, and lifecycle management, working closely with cross-functional teams across commercial, medical, regulatory, and clinical functions.

This is a leadership role on the commercial team that will own the go-to-market strategy, lifecycle planning, ensuring seamless collaboration across functions and support market access research ultimately driving meaningful patient impact and delivering strong business results.

Primary Responsibilities:

Brand Strategy & Tactical Execution:

• Develop integrated brand strategies and lifecycle activities to support differentiation and commercialization goals

• Drive disease area strategy, market segmentation, and product positioning based on unmet needs, competitive landscape, and evolving science

• Responsible for creating external (promotional/educational) communication materials for external use with customers (ECPs and Patients)

• Partner with Corporate Communications to support development of the Corp Communications tactics and messages as needed

• Lead the cross-functional workshops for the development of strategic and tactical plans for gildeuretinol

Competitive Strategy and Response:

• Assess emerging trends, market dynamics, and competitive activity to inform commercial decisions

• Lead competitive scenario planning and collaborate with medical, corp. comms, strategic planning and clinical to develop competitive response strategy

• Translate scientific and market insights from ECPs and patients (through market research, ad boards, etc.) into differentiated product strategy and value stories

• Evaluate strategic implications of evolving regulatory, pricing, and access landscapes globally

• Provide input into forecasting assumptions and evaluate ROI for activities

• Collaborate closely with regulatory, medical affairs, market access and corporate communications to ensure alignment of brand vision and execution

Program Team and key workstreams participation:

• Lead development/optimization of TPP

• Generate and communicate ECP/Patient insights to inform Program strategy

• Be the commercial voice on program team and inform decisions impacting commercialization

• Participate in the evidence generation, pubs planning and LCM strategy sub teams to represent the commercial POV

Qualifications:

• Education and Certification

• Advanced degree (MBA) in marketing/ business, or scientific degree preferred

• Requires 12+ years of experience or the equivalent combination of education and experience

• Skills and Key Success Factors:

• Entrepreneurship spirit with a passion to build, learn and evolve with the team

• Highly organized and detail oriented with a passion to deliver quality results

• Excellent verbal and written communication skills, with experience translating complex concepts for various audiences

• Demonstrated record of intellectual curiosity, innovation and creative problem solving with an entrepreneurial spirit

• Ability to lead fast-paced projects with a keen sense of urgency to get the job done well

• Evidence of "hands-on" experience and expertise

• Proven and successful track record as a team-player and collaborator in small working environments

• Highest levels of professionalism, confidence, personal values and ethical standards

Other Relevant Information:

• Travel: Able to travel up to 25% of time

Compensation

• Base Salary Range: $235K - $275K, with the actual contingent upon several factors such as the selected candidate’s education/work experience/training, and other factors (travel requirements, etc.)

• Discretionary Bonus: up to 25% of Base Salary, contingent upon meeting performance components

• Equity: initial grant of incentive stock options

• Benefits: Eligible to participate in group medical/dental/vision insurance plans; short- and long-term disability plans; life insurance; 401(K) plan; flexible time off policies and others. Eligibility and participation requirements vary by plan.

Alkeus Pharmaceuticals, Inc. is an equal opportunity employer and considers all qualified applicants for employment without regard to any characteristic protected by applicable law. We participate in E-Verify and conduct background checks as a part of our employment process.