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Small Molecule Purification Chemist

Confidential

San Diego, California permanent

Posted: January 30, 2026

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Quick Summary

We are seeking a Small Molecule Purification Chemist to join our team in San Diego, California. The ideal candidate will have expertise in purification techniques and a strong understanding of the life sciences industry.

Job Description

Cogent Scientific, an insourced contract research organization, is looking for the right people to accomplish our Mission: to build lasting partnerships that enable the life sciences industry to accelerate discovery and innovation in research and manufacturing.  We can offer you the chance to build on your skills and knowledge while working among experts in their fields and with cutting-edge instrumentation.

 

Cogent Scientific offers competitive pay (with relocation bonus as needed), attractive benefits (such as medical/dental/vision insurance; 401(k); parental leave; PTO and paid holidays; etc.) and an exciting work environment.  We aim to recruit the best people who stand out among their peers and embody our Core Values:

 

Client Focused: We only succeed when our clients succeed.

Outstanding: We deliver meticulous results through outstanding performance.

Good: We act ethically and morally.

Employee-Centric: We honor and support our employees.

Nimble: We are prepared to adapt in an ever-changing industry.

Team-Oriented: We collaborate with each other and with our clients.

We currently have a role available for a Small Molecule Purification Chemist.

 

Job duties include, but are not limited to:

Identifying, characterizing and purifying small molecule pharmaceutical compounds using analytical and chromatographic techniques (UPLC, HPLC, prep-LC, SFC, LC-MS, etc.).

Accustomed to purifying samples weighing between milligram - over 100 g samples; completing 50+ samples/wk.

This DOES NOT include protein, oligonucleotide and other large molecules.

Conducting preventative maintenance and troubleshooting on instrumentation as needed.

Rapidly developing unique and effective methods on LC and SFC.

Investigating LC-MS columns/methods for specific projects.

Working as a team with other chemists, external resources and data management groups.

Providing critical feedback to improve workflow and chemistry performance and implementation of best practices.

 

Job requirements include, but are not limited to:

MS in Biochemistry, Chemistry or related field with 3+ years of pharma laboratory experience outside of academia/academic research.  BS in Biochemistry or related field with 5+ years of experience will also be considered.

Extensive theoretical knowledge of UPLC, LC, LC-MS required, as well as hands-on experience with Waters and Agilent systems.

Excellent communication skills – verbal and written.

Works well both within a team and as an individual.

Demonstration of excellent team player and collaboration skills, very strong attention to detail, very strong problem-solving skills, a high level of learning agility, and the ability to work across functions.

The ideal candidate will be enthusiastic and self-motivated, with the leadership and communication skills necessary to operate effectively in a fast-paced multidisciplinary environment with flexibility and an adaptable approach to goal delivery.

 

This job posting will close by 2/1/2026 or when a candidate is identified, whichever comes first.

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