Site Director - Clinical Research

At Headlands Research, we are dedicated to enhancing clinical trial delivery within our communities. As a leading network of advanced clinical trial sites, we leverage cutting-edge technology and exceptional support services to broaden outreach and participation. Founded in 2018, our rapidly growing company currently operates 20+ sites across the US and Canada, with plans for further expansion.

📍 Location: Brownsville, Texas | 🏥 Site Name: Headlands Research Brownsville | 🕒 Full-Time | 🧪 Clinical Research

Are you a seasoned Clinical Research professional ready to lead at a higher level? Whether you’re a Senior/Lead CRC looking to step into site leadership or a current Site Manager ready for broader ownership, this is an opportunity to take full responsibility for site performance, team development, and clinical trial execution.

As Site Director, you’ll move beyond day-to-day coordination to lead the strategy, operations, and growth of a clinical research site—while still leveraging the deep operational expertise you built as a CRC.

Responsibilities:

• Lead the overall operational and financial performance of the clinical research site, including study execution, enrollment, and profitability

• Oversee all active clinical trials to ensure compliance with protocols, GCP, FDA regulations, and internal SOPs

• Monitor key performance metrics (e.g., enrollment, timelines, data quality) and implement improvements to drive site success

• Manage, coach, and develop a team of CRCs, research assistants, and site staff, fostering a high-performance and patient-focused culture

• Support hiring, onboarding, and ongoing performance management of site personnel

• Partner with internal teams to develop and execute patient recruitment strategies; monitor and optimize enrollment performance

• Build and maintain strong relationships with sponsors and CROs, ensuring high-quality delivery and repeat business

• Manage site budgets, staffing models, and resource allocation to optimize efficiency and financial outcomes

• Ensure audit readiness at all times; lead responses to audits, inspections, and quality findings

• Oversee regulatory documentation, source quality, and data integrity across all studies

• Identify operational challenges and implement scalable solutions to improve site performance

Requirements:

•

• 5+ years of clinical research site experience, with a strong foundation as a CRC

• Experience as a Site Manager, Lead CRC, or in a supervisory role strongly preferred

• Demonstrated ability to manage studies end-to-end, including enrollment and execution

• Prior experience leading, mentoring, or developing team members

• Strong knowledge of GCP, FDA regulations, and clinical trial operations

• Experience working with sponsors and CROs

• Proven ability to manage competing priorities in a fast-paced environment

• Strong business mindset with exposure to site metrics, budgets, or performance goals

• Bachelor’s degree preferred (or equivalent experience)

Why This Role?

• Expand your scope – Move from managing studies to leading an entire site

• Lead with credibility – Your CRC experience will directly shape how you coach and develop your team

• Drive real impact – Influence patient access to clinical trials and site-level success

• Grow your career – Clear path for advancement within a growing organization