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Senior Statistical Programmer II

AstraZeneca

US - Wilmington - DE permanent

Posted: March 6, 2026

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Quick Summary

AstraZeneca is a global, sci company that provides pharmaceuticals and healthcare products and services.

Job Description

The Senior Statistical Programmer II is a delivery focused role responsible for programming deliverables with quality and timeliness, following established standards and processes. This position requires high technical skills and thorough industry knowledge to independently perform the programming tasks while using judgement about seeking guidance in complex situations. They can be responsible for leading the programming deliveries of clinical studies or small to medium sized clinical projects and can lead cross-functional teams to deliver continuous improvement .

AstraZeneca is a global, science-led, patient-focused biopharmaceutical company that focuses on the discovery, development and commercialisation of prescription medicines for some of the world’s most serious disease. But we’re more than one of the world’s leading pharmaceutical companies.

Join the team dedicated to Oncology, with an ambition to eliminate cancer as a cause of death. It’s our big vision that unites and inspires us. With multiple indications and high-quality molecules at all stages of our innovative pipeline, we keep pushing forward. Fusing cutting-edge science with the latest technology to achieve breakthroughs. Backed by investment, we are aiming to deliver 6 new molecular entities by 2025.

We work on some of the most complex and interesting challenges. A fast-paced and agile team, we are empowered and trusted to innovate and experiment. With access to our extensive capabilities and comprehensive pipeline, you’ll be involved in countless submissions and a wide range of engaging projects along the complete drug development process.

Main Duties and Responsibilities

• Responsible for leading the programming deliveries of a clinical study or a small to medium sized and complex clinical project
• Implements statistical programming aspects of the protocol or clinical development program
• Ensures high quality is built into own deliverables and the quality delivered by other programmers
• Programs independently with high efficiency and quality
• Writes specifications and oversee completeness of relevant documentation
• Contributes to or drives the development of best practices to improve quality, efficiency and effectiveness within function
• Ensures compliance to standards and automation usage
• Plans and leads team activities and tasks
• Identifies, manages and communicates risk within the assigned studies and/or projects
• Works proactively with study team members including but not limited to the statistician, lead programmer, data manager and study leader
• Works cooperatively with contract programming providers
• Influences stakeholders by providing subject matter expertise on programming related items
• Contributes to or leads technical initiatives
• Employs project management practices in managing programming aspects of drug or technical projects

Essential Requirements

• You are focused on solving challenging problems through collaboration and partnerships. You are a specialist in your field, or aspire to be a specialist, and you know that the best results are achieved by utilising the strengths of every individual.
• Degree in Mathematics (i.e., Applied Math, Engineering, etc), Statistics, Computer Science, Life Science or equivalent
• Excellent programming skills including macro language
• Proficient knowledge of the clinical development process
• Thorough knowledge of industry standards
• Ability to manage relevant documentation.
• Ability to influence relevant stakeholders on Programming related items.

Desirable Requirements

• Ability to proactively manage concurrent activities within a study or part of project.

Why AstraZeneca?

At AstraZeneca we’re dedicated to being a Great Place to Work. Where you are empowered to push the boundaries of science and unleash your entrepreneurial spirit. There’s no better place to make a difference to medicine, patients and society. An inclusive culture that champions diversity and collaboration, and always committed to lifelong learning, growth and development. We’re on an exciting journey to pioneer the future of healthcare.

So, what’s next?

Are you already imagining yourself joining our team? Good, because we can’t wait to hear from you.

Are you ready to bring new ideas and fresh thinking to the table? Brilliant! We have one seat available and we hope it’s yours.

The annual base pay for this position ranges from $115,573.60 - $173,360.40. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted

06-Mar-2026

Closing Date

26-Mar-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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