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Senior Software Engineer

SOPHiA GENETICS

Bidart, Nouvelle-Aquitaine, France Hybrid permanent

Posted: March 10, 2026

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Quick Summary

We are looking for a Senior Software Engineer to join our team as a remote position for 3 days.

Job Description

Are you an experienced Software Engineer with a passion for building and improving scalable, high-performance systems? Are you looking for a team that embraces fresh ideas, encourages an agile approach, and ensures your voice is heard and your contributions truly make an impact?

If this sounds like you and you are driven by purpose, join the SOPHiA GENETICS Software Engineering team as our new Senior Software Engineer, and enable us to make a positive impact on the outcomes for cancer and rare disease patients worldwide.

This is a hybrid opportunity, requiring 3 days onsite our corporate office in Boston, MA or Bidart, FR. Please ensure that all CV/Resumes are submitted in English as we are an international company that uses English as our language of business.

Our Mission

We believe there is a smarter, more data-driven way to make decisions in healthcare and our cloud-native AI powered SOPHiA DDM Platform makes that vision a reality on a daily basis. You will have direct input to our mission to democratize data-driven medicine for the ultimate benefit of cancer and rare disease patients across the globe.

Your Mission

As our Senior Software Engineer, you will be responsible for developing, optimizing, and continuously improving core systems, while contributing to technical initiatives and ensuring solutions meet both business and technical requirements. The components you'll work on and own are essential to SOPHiA GENETICS’ DDM operations and enable integration with external hospital systems, unlocking the potential for processing of medical data into insights for oncologists at high volumes. These components span the technology stack and enable AI algorithms processing medical data to have a real-world impact via a robust and scalable architecture. Your expertise will ensure these components not only scale effectively but also remain efficient in terms of performance and cost, while maintaining overall system health. By implementing cutting edge clinical diagnostic workflows through system integrations at prominent healthcare institutions, you will have direct impact on the acceleration of progress of healthcare.

The value you bring

System Development & Improvement/ Maintenance:

• Design, develop, and continuously improve robust services and workflows that are scalable and efficient
• Implement enhancements based on evolving business and technical requirements.
• Ensure components are seamlessly integrated and perform reliably under workloads.
• Optimize system performance, resource utilization, and task execution times.

New Feature Development:

• Interact with internal and external stakeholders to understand and refine requirements
• Develop and implement new features and components to support changing business needs.
• Set up smart fully automated tests covering all use cases and requirements for long term maintainability

Deployment & Infrastructure Automation:

• Optimize deployment workflows, automate pipelines, and enhance infrastructure management for efficient and reliable application deployment.
• Contribute to improvements in system stability, minimizing downtime and ensuring seamless rollouts.

Monitoring & Observability:

• Implement and maintain monitoring systems to track performance and identify bottlenecks.
• Use observability tools like Grafana and Loki to improve system reliability and provide insights into operational health.


Requirements:
• Proficiency in Java for backend service engineering
• Extensive experience working on large-scale systems with microservice architecture
• Experience with React.js or other modern web UI development framework
• Experience in optimization of system performance, managing resources effectively and improving execution time - especially when dealing with very large data volumes
• Proficiency with databases like MySQL, MariaDB, and DuckDB, including design and query optimization
• Familiarity with Linux environments and GitLab for version control and CI/CD pipelines.
• Experience with scalable architecture, particularly in cloud environments and containerized infrastructure
• Familiarity with monitoring and observability tools like Grafana and Loki
• Experience in Micronaut for developing microservices and backend solutions is a strong plus.
• Experience with HL7 / FHIR protocols for healthcare interoperability is a strong plus
• Work experience in a direct customer facing role is a strong plus
• Knowledge of Kafka is a plus
• Experience in genomics is beneficial


Benefits:
You will be joining an organization with the patient at the heart of every decision and action, driven by purpose as we pursue exponential growth.

Business recognition and accolades include:

• World's most innovative companies (Top 10)
• World's smartest companies (Top 50)
• 100 Best Places to Work in Boston
• Top 10 European Tech Startup
• Top 10 European biotechs startup to watch
• Top 25 East-Coast Biotech to watch

Our benefits package is comprehensive, but varies internationally in-line with local standards and laws. You can discuss a full breakdown with us, but as a brief overview:

• Sickness and Accident coverage through Helsana
• Meal Vouchers at 90CHF PM with our partner cafeteria
• A fun and engaging work environment, with Rest & Entertainment space, full stocked free coffee machine and free fruit/snacks
• Free parking in an easy to access location
• A strong social committee whose purpose is to make SOPHiA GENETICs both enjoyable as well as rewarding
• As our global HQ, you’ll have direct interaction and exposure to senior leadership and our executive team locally

Our DNA

Like the strands of DNA itself, SOPHiA GENETICS and the team are deeply interconnected and reliant on each other to deliver. There are common threads across the team. Things that bind us together. Those things are Relentless Curious; Resilient & Nimble and Fearlessly Adventurous

Our Virtues

At SOPHiA GENETICS we established our 7 Virtues to clarify how our principles show up each day through action. We Decide; We Do; We Collaborate; We Innovate; We Empower; We Adapt and We Learn.

At the centre of our Virtues is our Mantra, We Care, which provides a constant reminder of the compassionate, benevolent, and hopeful nature of our mission and how it should be threaded through each of our Virtues and everything we do. Learn more about our DNA and Virtues on our Careers portal

The Process

We use the power of AI to help our partners make decisions. If you’re utilising AI in your search and application process, why not use some of these prompts, or read our AI guide.

‘What impact can I expect to have on the world by working at SOPHiA GENETICS?’

‘I have an interview with SOPHiA GENETICS. What should I know before I meet with them?’

‘I am a *job title* - What can SOPHiA GENETICS offer my career?’

Apply now with your CV and any supporting information.

Suitably qualified candidates will be invited through an interview and screening process where you will speak with members of our Talent Acquisition Team, the hiring leader alongside key colleagues and stakeholders from across the business. If you need additional support for accessibility, please contact our TA team for assistance.

We appreciate the value external partners can bring, but we operate a direct-hiring model and we are not looking to utilize agency support at this time. All hiring is controlled by Talent Acquisition, potential partners should liaise through TA and not our hiring teams please.

Starting Date: ASAP

Location: Boston, MA or Bidart, FR

Contract: Permanent

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