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Senior Scientist (Organ Perfusion)

Until

Bay Area permanent

Posted: December 17, 2024

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Quick Summary

We are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

Job Description

Until is a moonshot company building a “pause button” for biology. Our near-term focus is organ-scale reversible cryopreservation: preserving donated organs at subzero temperatures without ice formation, then rewarming them uniformly for transplant. By solving this grand challenge, we’re laying the foundation for whole-body reversible cryopreservation, giving patients a bridge to future cures.

To achieve our goal, we are assembling an interdisciplinary team to develop perfusion systems, cryoprotectant formulations, and vitrification and rewarming hardware.

We envision a future where no transplantable organ is lost to logistics, and no terminal diagnosis is final because patients can safely wait for future medicine to arrive.

About The Role
We are seeking a Senior Scientist to join as a leader on our whole organ preservation team. You will have large domain of ownership and play a vital role in shaping the company's organ transplant research program. You will apply your expertise in organ perfusion, preservation, viability assessment, and transplant to make successful large organ cryopreservation a reality.

You will have the opportunity to collaborate with scientists and engineers across the company on variety of methods inspired by first principles of biology, physics, and chemistry. Creative scientific engagement is a requirement of the role, and new avenues for discovery and optimization are continuously supported.


Responsibilities:
• Implement pig organ ex-vivo viability evaluation protocols, including perfusion, histology, omics, etc.
• Ability to comfortably execute familiar assay protocols as well as identifying and implementing unfamiliar protocols to diagnose damage
• Propose adjustments to cryopreservation protocol to optimize the health of organs
• Experience working with ex vivo kidney and / or heart perfusion and viability assessment is a plus


Qualifications:
• You’ve completed a PhD in STEM, ideally in the field of organ preservation or transplant, or otherwise have significant (4+ years) experience working as a scientific leader in an industry context.
• You have demonstrated a passion for rapid problem solving and exploration of novel topics / protocols, demonstrated success working through hard problems.
• Desire to work in a laboratory setting to apply your expertise.
• You demonstrate agency, problem solving, passion for discovery, and a drive to push the boundaries of science through meaningful involvement in an ambitious project.


Benefits:
• A unique opportunity to learn new skills, develop impactful technology, and work with an ambitious team
• Medical and dental insurance coverage
• Flexible time off and paid holidays
• Competitive compensation package, including salary and equity
• Access to a 401(k) retirement savings plan


As an equal opportunity employer, Until is committed to providing employment opportunities to all individuals. All applicants for positions at Until will be treated without regard to race, color, ethnicity, religion, sex, gender, gender identity and expression, sexual orientation, national origin, disability, age, marital status, veteran status, pregnancy, or any other basis prohibited by applicable law.

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