Senior Scientist II (Project Leader/Principal Investigator) – LC-MS/MS Bioanalysis (PK/PD)

Confidential

Macclesfield, Cheshire permanent

Posted: April 2, 2026

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Quick Summary

We are seeking a Responsible Scientist to lead LC-MS/MS bioanalytical studies under GLP and GCP, ensuring scientific integrity, regulatory compliance, and successful study delivery.

Required Skills

Genomic Analysis Method Development Validation Sample Analysis Data Review Regulatory Compliance Problem Solving

Job Description

Role Overview

We are seeking a Responsible Scientist to lead LC-MS/MS bioanalytical studies, ensuring scientific integrity, regulatory compliance, and successful study delivery.

Key Responsibilities

Act as scientific lead for LC-MS/MS bioanalytical studies conducted under GLP and GCP

Oversee method development, validation, and sample analysis

Review and interpret analytical data to ensure quality and compliance

Lead investigations into analytical issues and implement corrective actions

Ensure studies meet regulatory requirements and internal standards

Act as primary scientific contact for clients

Prepare, review, and approve study documentation and reports

Technical Expertise

Strong experience in LC-MS/MS method development and validation

Understanding of sample preparation techniques and analytical workflows

Ability to troubleshoot issues such as matrix effects, sensitivity, and assay variability

Qualifications and Experience

MSc or PhD in Analytical Chemistry or related field

5 to 10 or more years of LC-MS/MS bioanalysis experience

Experience leading regulated studies in a GLP/GCP environment

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