Senior Scientist II, Molecular & Cellular Pharmacology, Discovery Psychiatry

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

AbbVie Discovery Neuroscience team seeks a collaborative senior scientist who will lead from the laboratory bench to support advancement of psychiatry assets. In this onsite role, you will leverage your significant demonstrated experience in molecular and cellular pharmacology, in vitro human-derived cellular models, and ex vivo sample analysis to propose/evaluate new approaches and carry out well-matched approaches for scientific questions supporting advancement of assets through stage-gate transitions.  

You will be expected to have strong communication skills, be agile, operate comfortably with ambiguity on formal and informal teams, and work with a sense of urgency and accountability to advance projects efficiently and compliantly. Opportunities will exist to contribute to target validation and progression, collaborate across AbbVie sites, present your work, and mentor scientists. We’re excited to see how you can help AbbVie develop life-changing psychiatric therapeutics for patients. 

Responsibilities

• Proactively translate department/project team scientific questions into well-designed experiments, utilizing internal and external resources 
• Explore multiple technical options for approach, quality, feasibility, efficiency and present recommendations at project team or group meetings 
• Set up and carry out novel molecular and cellular assays/models to support SAR and understanding of target biology in context of project team goals & transitions  
• Document protocols and results in databases and electronic laboratory notebook, contributing to formal study reports per business need 
• Uphold impeccable research-related & corporate compliance standards 
• Collaborate across the organization; Mentor/matrix manage junior scientists 

• Bachelor’s Degree or equivalent education and typically 12+ years of experience, Master’s Degree or equivalent education and typically 10+ years of experience, PhD and typically 4+ years of experience.
• Possess thorough theoretical and practical understanding of own scientific discipline.
• Effective writer and communicator of research or other regulatory materials.

Desired Qualifications: 

• Significant experience with running and interpreting pharmacological studies, human iPSC-neuron culture, clonal cell line culture, equipment/assay selection and development 
• Growth mindset with strong organizational, communication, and collaboration skills 
• Demonstrated ability to learn and master new experimental techniques 
• Attention to detail with ability to see big picture, multitask and work within timelines 
• Pharmaceutical industry drug discovery experience 
• Experience with endpoints related to neurotransmitters, receptor signaling, trafficking, neuroplasticity, proteomics.
• Experience with medium to high throughput technology and techniques such as electronic dispensing equipment/robotics, AlphaLISA, HTRF, ELISA, MSD, qPCR, capillary Western, FLIPR, kinetic/endpoint assays, high-content imaging; engages vendors/reads manuals 
• Ex vivo sample assay design, processing, and analysis experience 
• Additional CNS iPSC-derived cell experience, encompassing multiple cell types 
• Psychiatry therapeutic area experience 
• Familiarity leveraging AI tools to improve productivity 

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this postingbased on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more orless than the posted range. This range may be modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our long-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission,incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paidand may be modified at the Company’s sole and absolute discretion, consistent with applicable law. ​

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more:

https://www.abbvie.com/join-us/reasonable-accommodations.html