Senior Scientist I, Precision Medicine Oncology Genomics

About AbbVie

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on LinkedIn, Facebook, Instagram, X and YouTube.

We are seeking a highly motivated Senior Scientist with a strong background and a proven track record in single-cell and spatial genomics, molecular and cell biology. The successful candidate will join our dynamic team at AbbVie Bay Area (South San Francisco, CA), contributing both within the Oncology Translational Research group and in cross-functional R&D teams to support cutting-edge genomic research and mechanism / biomarker discovery for our drug development pipeline.

Responsibilities:

• Independently design, execute, and analyze complex genomic profiling experiments- including single-cell RNA-Seq, CITE-Seq, spatial transcriptomics/proteomics, and long-read sequencing.
• As the primary scientific driver, support preclinical and clinical biomarker discovery, elucidation of drug sensitivity and resistance mechanisms, informing clinical decisions to advance the AbbVie oncology pipeline.
• Proactively identify technical artifacts, interpret quality control results, optimize assay performance, and ensure high quality and reproducible data delivery on timely deadlines.
• Bridge the gap between genomic data and biological insights with strong background in tumor and immune cell biology.
• Collaborate with cross-functional teams - including clinical biomarkers, bioinformatics, statistics and pathology to ensure seamless alignment on scientific rationale, data generation and data interpretation workflows.
• Stay at the forefront of the single-cell and spatial genomics field by surveying, evaluating, testing and validating novel scientific methodologies.
• Present work plans and interim QC analyses with clarity and precision to cross-functional stakeholders via formal written reports and verbal updates.
• Work independently as well as part of a multidisciplinary team in an exciting, fast-paced environment.

Required Qualifications:

• Bachelor’s Degree or equivalent education and typically 10 years of experience, Master’s Degree or equivalent education and typically 8 years of experience, PhD and no experience necessary
• Precision and broad technical expertise in molecular biology and cell biology assays (e.g., DNA and RNA extraction, qPCR, RNA-Seq library prep, single cell RNA-Seq and flow cytometry analysis). 
• Strong laboratory and organizational skills; ability to manage and execute multiple projects concurrently.
• Proven track record of scientific writing skills and strong verbal communication skills.
• Excellent critical thinking and demonstrated productivity in interdisciplinary and dynamic team setting.
• Proficiency in flow cytometry and single-cell/CITE-Seq experiments in academic or industry setting is preferred.

Preferred Qualifications:

• Demonstrated excellence and deep expertise in single-cell and spatial genomics is strongly desired.

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law: ​

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at thetime of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographiclocation, and we may ultimately pay more or less than the posted range. This range may be modified in the future. ​

• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.​

• This job is eligible to participate in our short-term incentive programs. ​

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability ofany bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company'ssole and absolute discretion unless and until paid and may be modified at the Company’s sole and absolute discretion, consistent with applicable law. 

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community.  Equal Opportunity Employer/Veterans/Disabled. 

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