Senior Research Scientist, Evidence Synthesis

Do you consider yourself a self-starter with a real passion for projects involving innovative methods in evidence synthesis? Do you love collaborating, moving the ball forward and rolling up your sleeves? We are growing and seeking a Senior Research Scientist with technical experience in systematic literature reviews and/or indirect treatment comparisons (e.g. NMA, MAIC, STC) for the purposes of health technology assessment submissions. We offer opportunities to work 100% remotely from Canada or the US.

Our culture is similar to that of a start-up, but in a well-funded established global portfolio organization. We pride ourselves on being leaders with vision in our field! Below are some examples of recent work we have published as part of our efforts to support our clients:

• Cope S, Chan K, Jansen JP. Multivariate network meta‐analysis of survival function parameters. Research synthesis methods. 2020;11(3):443-456. https://doi.org/10.1002/jrsm.1405

• Freemantle N, Xu Y, Wilson FR, et al. Network meta-analysis of immune-oncology monotherapy as first-line treatment for advanced non-small-cell lung cancer in patients with PD-L1 expression ≥50. Ther Adv Med Oncol. 2022; 14:17588359221105024. https://doi.org/10.1177/17588359221105024

• Watts, JM, Wang, ES, Jonas, BA, Wilson FR, et al. Matching-Adjusted Indirect Comparison of Olutasidenib and Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Relapsed/Refractory Acute Myeloid Leukemia. Adv Ther. 2026;43:1802–1815. https://doi.org/10.1007/s12325-026-03522-6

• Keeping ST, Cope S, Chan K, et al. Comparative effectiveness of nivolumab versus standard of care for third-line patients with small-cell lung cancer. J Comp Eff Res. 2020;9(18):1275–1284. https://doi.org/10.2217/cer-2020-0134

Senior Research Scientists collaborate across a broad portfolio of sophisticated evidence synthesis projects in a multi-level team structure. Responsibilities include development of deliverables (e.g. study protocols and technical reports), handling day-to-day client communications, as well as delegating and overseeing tasks completed by junior researchers. This position will complete complex job responsibilities independently as well as provide mentorship and direction for others in delivering project work.

Essential functions for this role are:

• Subject Matter Expertise/Domain Knowledge

• Demonstrates understanding of the pharmaceutical industry, medical affairs, and requirements for health technology assessments

• Sufficient understanding of relevant methods to be able to oversee systematic literature reviews (clinical, economic, and/or health-related quality of life) and/or quantitative evidence synthesis studies

• Can identify considerations relevant to the synthesis of available evidence and communicate these within deliverables (e.g., feasibility assessments, statistical analysis plans)

• Deliverable Creation

• Develops client-ready deliverables including protocols, statistical analysis plans, technical reports, and slides

• Strategic Direction

• Contributes to short-term resourcing discussions

• Project Management

• Manages the delivery of components of projects by collaborating with other staff members to ensure high quality outputs

• Helps ensure timely delivery and financial performance of projects or project subcomponents

• Estimates required hours and identifies challenges early on and communicates any changes as well as viable solutions to project lead if necessary

• Client Management

• Reviews update slides/minutes and actions for overall study and viewed by client as independent researcher for specific study or component(s)

• Leads client calls and responds to emails, inviting input from senior team members with methodological/subject matter expertise where appropriate

• Line Management/Team Development

• Creates development plans and acts as a mentor for direct reports

• Business Development

• Contributes to development of proposals and presentations under guidance of more senior team members with methodological/subject matter expertise

• May also participate in meetings related to new business, including concept ideation

Minimum required experience for this role is:

• Master’s degree in a subject related to health services research e.g., health economics, public policy, health policy, epidemiology, biostatistics, public health, or science (biology/biochemistry etc.)

• 4-6 years’ professional experience

Core competencies required for this role are:

• Willingness and desire to learn and share knowledge

• Excellent oral and written communication skills

• Proficiency with Microsoft Office and EndNote

• Proficiency in R/R Shiny advantageous

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Precision Medicine Group is an Equal Opportunity Employer. Employment decisions are made without regard to race, color, age, religion, sex, sexual orientation, gender identity, national origin, disability, veteran status or other characteristics protected by law.

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