Senior Research Associate, Preclinical and Clinical Biomarkers

About Apogee Therapeutics

Founded in 2022, Apogee Therapeutics, Inc. (Ticker: APGE) is a well-funded, Nasdaq listed company that offers the opportunity to work in a fast-paced, highly dynamic environment. At Apogee, you can actively contribute to shaping the company culture, take on various roles and responsibilities, and grow professionally.

Apogee Therapeutics, Inc. is a biotechnology company seeking to develop differentiated biologics for the treatment of atopic dermatitis, chronic obstructive pulmonary disease and other inflammatory and immunology indications with high unmet need. Our antibody programs are designed to potentially overcome limitations of existing therapies by targeting well-established mechanisms of action and incorporating advanced antibody engineering to optimize half-life and other properties. We seek to reshape the current standard of care for inflammatory and immune diseases because we believe people living with these diseases deserve the best possible treatment, and we refuse to stop at “good enough.”

We are a fast-paced company committed to building an exceptional company culture, founded on our C.O.R.E. values: Caring, Original, Resilient and Egoless.

If this sounds like you, keep reading!

Role Summary
The Department of Research and Translational Medicine is seeking a highly motivated and detail-oriented Research Associate/Senior RA, Preclinical and Clinical Biomarkers to support our growing research and development efforts. The ideal candidate will have a strong background in immunoassay development and qualification, with hands-on experience in ELISA and MSD-based assays. Experience handling and testing clinical patient samples, with a strong understanding of best practices for sample integrity and compliance. This role requires a collaborative team player who can interpret complex data sets, implement best practices, and maintain high standards of quality and documentation.

Key Responsibilities

• Design, develop, and qualify immunoassays including ELISA and MSD platforms to support research and product development.

• Experience with assay automation preferred but not required.

• Analyze and interpret complex biological data sets with precision and scientific rigor.

• Apply best practices to minimize assay variability and ensure reproducibility.

• Maintain detailed and accurate records of experimental procedures and results in accordance with quality control standards.

• Maintain the inventory of samples and associated paperwork according to our operating procedures

• Assists with identifying needs and sourcing of reagents, samples, and other critical materials

• Collaborate cross-functionally with other scientists and departments to support project goals.

• Contribute to troubleshooting and optimization of assay protocols.

• Ensure compliance with internal SOPs and regulatory guidelines.

Ideal Candidate

• Bachelor’s degree in Biology, Molecular Biology, Biochemistry, or a related scientific discipline with 3–5 years of industry experience, or a Master’s degree with at least 2 years of relevant experience.

• Demonstrated expertise in immunoassay development and qualification, specifically ELISA and MSD.

• Strong analytical skills with the ability to interpret complex data and draw meaningful conclusions.

• Experience implementing quality control measures and maintaining scientific documentation.

• Excellent communication and organizational skills.

• Ability to work independently and as part of a collaborative team in a fast-paced environment.

• Ability and willingness to travel including a minimum of 2 times per year for company-wide meeting

• Ability to work onsite up to 5 days per week in the Apogee lab located in Boston, MA

The anticipated salary range for candidates for this role will be $95,000- $110,000 per year. The final salary offered will depend on several factors, which may include, but is not limited to relevant years of experience, educational background, and geography.

What We Offer

• A great culture, grounded in our C.O.R.E. values: Caring, Original, Resilient and Egoless

• Opportunity to work in a fast-paced, highly dynamic environment where you help shape the culture and company, wear multiple hats, and learn quickly

• Market competitive compensation and benefits package, including base salary, performance bonus, equity grant opportunities, health, welfare & retirement benefits

• We provide competitive time off, including three weeks PTO, two one-week company-wide shutdowns a year and dedicated paid sick leave

• Commitment to growing you professionally and providing access to resources to further your development

• Apogee offers regular all team, in-person meetings to build relationships and problem solve

E-Verify Participation: As part of the I9 verification of authorization to work in the US, Apogee participates in E-Verify. To learn more about E-Verify please review this poster.

Apogee Therapeutics is proud to be an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected Veteran status, age, or any other characteristic protected by law.

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It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.