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Senior Payroll & Benefits Specialist

Arrowheadpharmacareers

Pasadena, California, United States (Pasadena, CA) permanent

Posted: May 7, 2026

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Job Description

Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

Arrowhead Pharmaceuticals is seeking a highly motivated Senior Payroll & Benefits Specialist to join our People Services & Culture team. Reporting to the Associate Director of Payroll & Benefits, this role will be responsible for assisting with the end-to-end processing of biweekly payroll and day-to-day benefit support for employees across four locations: Pasadena, CA; San Diego, CA; Madison, WI; and Verona, WI. The Senior Specialist will also process off-cycle payrolls as needed.

In addition, this individual will oversee the administration of daily and quarterly equity compensation transactions, including processing new grants, stock option exercises and restricted stock unit (RSU) activity. Collaboration with the Accounting team and broader People Services & Culture department will be essential to ensure accuracy and compliance. In addition to administration of equity compensation, the Sr Specialist will support the broader People Services & Culture team in general HR related areas.

This is a full-time, onsite position at Arrowhead’s Corporate Headquarters in Pasadena, CA.

Responsibilities

• Back up for all payroll activities, including calculating final pay for upcoming terminations and processing their separation through ADP WFN.

• Creating and maintaining equity compensation checklists, routing as needed in a timely manner for completion, and closing out checklists once complete.

• Key player in managing company’s equity plan

• Help to ensure equity processes comply with federal, state and local regulations

• Backup for reviewing and processing biweekly timecards; following up with employees and supervisors as needed.

• Maintain electronic equity filing systems.

• Backup for tracking or managing benefits

• Conduct audits as needed to ensure all employee changes and pay data has been entered

• Provide benefit support as needed

• Provide system support and focus on process improvement on all areas of HR

• Support general HR/People Services tasks as needed

Requirements

• 4 recent years of payroll & benefits experience.

• Associate degree.

• Ability to follow verbal and written instructions.

• Must be able to keep up with a fast past while maintaining attention to detail.

• Ability to gather, analyze and interpret information for completeness and accuracy, and excellent organizational skills.

• Recent experience with current version of ADP WFN and advanced Excel skills.

• Knowledge of wage and hour laws related to payroll.

• Knowledge of equity compensation administration is a plus.

• Proficient in Microsoft Office suite.

• Strong communication skills (oral & written); ability to effectively interact with others at all levels – within and outside of finance.

• Flexibility to put in extra hours during critical times.

• Strong time management with the ability to work independently and in a group setting.

Preferred

• Bachelors degree

California pay range
$85,000—$110,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

Candidates must have current, valid authorization to work in the country where this role is located.

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