Senior Manager, Sales Operations

SENIOR MANAGER, SALES OPERATIONS

At Day One, we are focused on advancing first- or best-in-class medicines for childhood and adult diseases with equal intensity. We were founded to address the lack of new therapies resulting from the traditional drug development model, that has left children with cancer and their families waiting too long for new, life-changing treatments. Our aim is to accelerate better, targeted treatments so patients of any age can look forward from ‘day one’ to the future they’ve envisioned.

POSITION SUMMARY:

The Senior Manager, Sales Operations will play a critical role in supporting the ongoing commercial success of our therapy for pediatric low-grade glioma. This individual will serve as a key partner to the field organization, driving performance insights, enabling data-driven decision-making, and optimizing sales execution in a highly specialized rare-disease oncology environment.

Reporting to the Senior Director, Commercial Analytics, the ideal candidate brings deep experience in sales operations, strong analytical capabilities, fluency working with commercial data sources, and the ability to effectively partner with field sales leadership. This role is highly cross-functional and requires strategic thinking, technical proficiency, and exceptional communication skills.

This position has the potential to be fully remote although SF Bay area with ability to be in home office 2 days/week a plus. Occasional travel will be required for in person meetings.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

Field Analytics & Reporting:

• Develop, automate, and maintain dashboards and reporting Applications for field sales leadership and field teams.

• Provide actionable insights on field performance, geographic trends, physician and account level analytics, and patient enrollment dynamics.

• Provide regular leadership updates in sales performance and IC rankings

• Partner with field advisory teams to evaluate and enhance reporting deliverables.

Patient-Finding & Data Enablement

• Partner with Commercial Operations and Sales Leadership to support patient identification strategies using claims data, EMR data, specialty pharmacy data, and other rare-disease data assets.

• Create territory-level patient opportunity assessments and support field deployment of targeting tools.

Incentive Compensation (IC)

• Design, manage, and administer incentive compensation plans and contests for field teams, ensuring fairness, motivation, and alignment with strategic objectives.

• Partner with Field Advisory teams to develop and create advocacy with IC plans.

• Model IC scenarios, process quarterly IC validation, manage payouts, and ensure compliance with policies and legal guidelines.

• Partner closely with IC Steering Committee to ensure alignment on plan performance and communication.

Customer-Level Insights

• Generate insights at the healthcare provider (HCP), institution, and network level to guide targeting, segmentation, pull-through and account planning.

• Translate complex data trends into actionable recommendations for field leadership.

• Monitor customer behavior, adoption patterns, and market dynamics.

CRM Ownership & Optimization

• Serve as commercial business owner for the CRM (e.g., Veeva), ensuring field usability, data integrity, and continuous enhancement.

• Translate field requirements into CRM configurations, workflows, and reporting improvements.

• Train, support, and develop CRM best practices across the field team.

Cross-Functional Leadership

• Collaborate closely with Sales, Marketing, Market Access, Data Management and IT teams to align operational processes and data strategy.

• Serve as a thought partner to sales leadership on execution strategy, performance diagnostics, and field enablement.

• Support launch readiness activities, process buildout, and ongoing commercial evolution.

QUALIFICATIONS

Required

• Bachelor’s degree in Business, Analytics, Life Sciences, or related field; advanced degree a plus.

• 5–7+ years of experience in pharmaceutical/biotech Sales Operations and/or Commercial Analytics.

• Strong analytical and quantitative skills with proficiency in Excel, BI tools (DOMO, Tableau, Power BI, Qlik, etc.), and CRM systems (Veeva preferred).

• Experience supporting field sales teams and collaborating directly with field leadership.

• Demonstrated ability to synthesize complex data into clear insights and recommendations.

• Solid understanding of U.S. pharmaceutical data sets (e.g., claims, specialty pharmacy, HUB, distribution).

• Strong project management, communication, and stakeholder engagement skills.

Preferred

• Experience in rare disease, oncology, or small-volume/high-complexity product environments.

• Comfortable working in a fast-paced, build-as-you-go environment associated with emerging biotech.

• Familiarity with patient-finding methodologies and advanced targeting analytics.

• Prior experience managing or administering incentive compensation programs.

Key Attributes

• Curious and strategic thinker with strong attention to detail.

• Highly collaborative and comfortable engaging with senior leadership and field stakeholders.

• Self-starter who thrives in ambiguity and can build processes from the ground up.

• Exceptional communication skills—able to translate data into compelling, actionable stories.

The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification.

INTERVIEW INTEGRITY

At Day One, we expect each candidate to engage authentically, representing their true qualifications and experiences. As part of our screening process, we will conduct several interviews and background verification. This ensures candidates have the skills they claim and align with our values. We are excited to learn more about you and to create a genuine experience for everyone.

COMPENSATION AND BENEFITS

The salary range for this position is $170,000 - $180,000. Day One considers a range of factors when determining base compensation. These considerations mean actual compensation will vary.

Please visit https://www.dayonebio.com/benefits to see our competitive benefits.

DISCLAIMER

Day One Biopharmaceuticals is committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law.

We are unable to sponsor or take over sponsorship of any applicant work visas at this time.

Recruitment & Staffing Agencies: Day One Biopharmaceuticals does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Day One Biopharmaceuticals or its employees is strictly prohibited unless contacted directly by Day One Biopharmaceutical’s internal HR team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Day One Biopharmaceuticals, and Day One Biopharmaceuticals will not owe any referral or other fees with respect thereto.