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Senior Manager, People Operations & Total Rewards

Iterativehealth

Cambridge, Massachusetts, United States, New York, New York, United States (Cambridge, New York) Remote permanent

Posted: February 23, 2026

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Quick Summary

We are seeking a Senior Manager for our Gastrointestinal (GI) and Hepatology research sites, where you will be responsible for the success and growth of our partner sites by empowering them with tech-enabled services.

Job Description

Iterative Health is a healthcare technology and services company powering the acceleration of clinical research to transform patient outcomes. The Iterative Health Site Network is a premier network of 70+ clinical research sites across US and Europe accelerating the path to market for gastrointestinal (GI) and hepatology novel therapies. Our focus is on driving the success and growth of our partner sites by empowering them with tech-enabled services. By combining deep expertise in clinical trials with cutting-edge AI, we empower research teams and study sponsors to expand and expedite access to novel therapeutics for patients in need.

As the Senior Manager, People Operations & Total Rewards, you’ll play a critical role in building, optimizing and scaling the People Operations function in support of the Iterative Health network. This is a hands-on, strategic role focused on integrating newly acquired businesses, building, implementing and harmonizing best-in-class HR operational systems, processes and programs, and supporting leaders across a highly distributed hourly and salaried, growing multi-site network and corporate team.

Success Criteria:

This role requires a process and infrastructure builder as well as a functional expert within HR systems, compensation models, benefits (total rewards) and analytics. Experience growing and scaling a field-based, multi-location workforce in the U.S. and globally is preferred. You will serve as both a strategic partner and tactical operator, ensuring compliance, standardization, efficiency, and consistency while empowering people leaders across the platform.

The ideal candidate is hands-on, detail-oriented, analytical and equally comfortable solving immediate operational needs while balancing building scalable processes for the future. They will continuously scan for better tools, processes, and practices to elevate the employee experience and improve operational efficiency and will play a key role in shaping a best-in-class People Operations function that scales with our growth.

Key Responsibilities:

• People Ops Infrastructure: Develop plan around consolidating and harmonizing disparate HR systems and processes towards a unified approach under one holistic HRMs. Lead system integration of new HRMs system, defining business requirements and working with vendor integration team and IH stakeholders to ensure seamless adoption and usage across the company.

• HR M&A Integration: Partner with operations leadership, finance and HRBPs to conduct due diligence and assess total rewards analysis to ensure seamless onboarding and integration of acquired companies’ employees into IH while harmonizing benefits, policies and procedures.

• Lead Total Rewards strategy development, leveraging external brokers, finance and internal stakeholders to support optimizing current benefit plan’s structure, competitiveness and cost considerations in time for open enrollment period.

• Systems & Data: Lead the ongoing ownership and management of an HRIS platform, ensuring data integrity, efficiency, and scalability across multiple site locations. Develop people analytics and reporting mechanisms to provide the business with a scorecard on key KPIs and HR metrics on a regular basis.

• Policy & Compliance: Develop and implement HR policies, procedures, and documentation aligned with federal, state, and local labor laws across multiple operating locations, including globally.

• Develop and work with operations and HRBPs to implement compensation strategies for both a field based hourly workforce and a high-tech salaried corporate workforce, aligning processes and policies across the enterprise.

• Oversee payroll processes (as partner with finance), benefits enrollment, and vendor management to deliver seamless employee experience.

• Employee Experience: Partner with local leaders to promote a positive culture, engagement, and retention, ensuring people-operation and total rewards initiatives align and scale with business strategy.

Ideal Profile:

• 7–10+ years of HR/People operations and total rewards experience with a high-growth, start up environment or investor-backed portfolio company who has navigated scaling and building structure and process to transform its evolution.

• Proven experience building and implementing HR processes and systems in multi-entity or acquisitive growth environment.

• Experience within the healthcare services or pharmaceutical, biotech industry, particularly with exposure to multi-site clinical research operations.

• Experience with managing HRIS platforms (e.g. BambooHR, ADP, Rippling) and implementing larger, more sophisticated, holistic HRM systems such as Workday or UKG.

• Experience evaluating total rewards programs and managing benefits administration across enrollment, renewals, vendor relationships, employee communications, and ongoing issue resolution.

• Demonstrated experience aligning compensation programs that are tied to business results across a growing and changing organization.

• Highly analytical and comfortable with data gathering and data analysis. • Hands-on operator with the ability to balance structure building with day-to-day execution. • Excellent interpersonal, communication, and relationship-building skills; capable of working effectively with diverse leadership teams as well as hourly site clinical staff.

• M&A integration experience is highly preferred.

• Comfortable working in a hybrid/distributed team environment.

New York pay range
$140,000—$170,000 USD

At Iterative Health, we’re actively working towards creating an environment that is representative of the diversity of patients our technology serves. We are focused on building an equitable and inclusive culture, and by extension, hiring process. If you require any accommodations to make the application process or interviewing experience more accessible to you, please contact [email protected].

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