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Senior Manager, North America Supply Chain

Ultragenyxpharmaceutical

Novato, CA Hybrid permanent

Posted: April 15, 2026

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Quick Summary

We're seeking a Senior Manager to lead our North America supply chain, responsible for optimizing logistics and supply chain operations.

Job Description

Why Join Us?

Be a hero for our rare disease patients

At Ultragenyx, we fundamentally believe that taking real impactful action to care for the needs of patients and our people is always the right thing to do. To achieve this goal, our vision is to lead the future of rare disease medicine. For us, this means going where other biopharma companies won’t go – challenging the status quo and creating a new model that advances our field so more patients and caregivers can benefit from life-changing treatments. We do this by following the science, applying a novel rapid development approach, making innovative medicines at fair and reasonable prices, and creating a collaborative ecosystem to reach patients in ways that are most meaningful for them.

Our commitment and care for patients extends to our people, so culture is an essential cornerstone for Ultragenyx. We remain continuously focused on creating a supportive and inclusive environment of profound learning and growth – so employees can thrive in all areas of their lives, in and outside of work. Ultimately, we want to be an organization where we would be proud for our family, friends and children to work.

If you want to have a meaningful impact, do the best work of your career, and grow a lot, both professionally and personally, come join our team.

Position Summary:

ultrafocused – Work together to fearlessly uncover new possibilities

The focus of this position is on the Distribution Operations within North America, including the oversight of vendor performance involved in the distribution operations, the set-up of new distribution lanes in line with trade compliance and regulations, management of orders through delivery to customers, as well as continuously improving processes related to the Distribution Operations. This role closely liaises with global and regional functions (examples: Commercial, Medical Affairs, Finance, Regional Planning, Global Logistics, and Quality). The position acts as back-up for the Supply Chain EMEA & APAC (Sales Operations and Inventory Planning) and to the Regional Supply Chain Head.

Work Model:

Flex: This role will typically require onsite work 2-3 days each week or more depending on business needs. In many locations, the business will set certain days each week that Flex employees are required to be onsite.

Responsibilities:

· Oversee and ensure the Distribution Operations are performed in compliance with trade & GxP regulations, as well as internal requirements and policies

· Oversee the Gene Therapy order coordination through delivery to customer and providing technical guidance as needed.

· Effectively collaborates and communicates with the NA Commercial organization to ensure their needs are incorporated into the supply plan.

· Act as Vendor Relationship Manager to the Distribution Partners in the Region utilizing respective KPIs, including monitoring spend and contribution to the budgeting process.

· Supports cross-functional projects, including NA commercial product supply, product launch readiness, and Gene Therapy make to order process.

· Set-up new supply lanes with internal and external business partners, and act as project manager including change control in our Quality Management System

· Identify and implement continuous improvement initiatives (example: temperature monitoring in transportation, and optimization of transportation costs).

· Oversee month-end closing activities within Distribution Operations. This includes acting as key contact to Tax & Finance related to distribution transactions and Oracle reconciliation.

· Perform order entry and execution of orders in our ERP system (Oracle).

· Manages contracts/SOWs/purchase orders with 3PLs for storage and distribution and other related supply activities.

Requirements:

· A Bachelor’s degree in a related field (Supply Chain, Business) or equivalent

· 7+ years of progressively more challenging experience in Supply Chain roles within GxP regulated industries

· Background in managing cross functional teams, demand/supply alignment, and inventory management

· Strong understanding of pharmaceutical industry procedures and regulations including cGMPs, cGDP and other regulatory requirements

· Strong understanding of working ability in a Quality Management System (Veeva), with experience in managing Quality Events, Change Controls and investigations

· Effective communication & stakeholder management at different levels: verbal, written, and presentations

· Demonstrated ability to lead cross-functional groups and external partners to achieve business objectives in a fast-changing environment

· Experience with ERP (Oracle and Kinaxis) systems as well as proficiency with the Microsoft Office Suite (Excel, Word, PowerPoint, Visio, Power BI, and Outlook)

· Available for off-hours questions and calls

· Ability to travel throughout the region up to 15%

#LI-CT1 #LI-Hybrid

The typical annual salary range for this full-time position is listed below. This range reflects the characteristics of the job, such as required skills and qualifications and is based on the office location noted in this job posting. The range may also be adjusted based on applicant's geographic location.

This position is eligible for annual bonus and equity incentives. Actual individual pay is determined by demonstrated experience and internal equity alignment.

Pay Range
$159,600—$197,200 USD

Full Time employees across the globe enjoy a range of benefits, including, but not limited to:

· Generous vacation time and public holidays observed by the company

· Volunteer days

· Long term incentive and Employee stock purchase plans or equivalent offerings

· Employee wellbeing benefits

· Fitness reimbursement

· Tuition sponsoring

· Professional development plans

* Benefits vary by region and country

Ultragenyx Pharmaceutical is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital and veteran status, and any other status or classification protected by applicable federal, state, and/or local laws. Reasonable accommodation will be provided for all protected statuses or classifications protected by applicable law, including individuals with disabilities, disabled veterans, for pregnancy, childbirth, and related medical conditions, and based on sincerely held religious beliefs. Applicants can request an accommodation prior to accepting a job offer. If you require reasonable accommodation in completing this application, or in any part of the recruitment process, you may contact Talent Acquisition by emailing us at [email protected].

See our CCPA Employee and Applicant Privacy Notice.

See our Privacy Policy.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

Note to External Recruiters: All candidate activity and open positions are managed strictly through our Human Resources Department. Our Human Resources Department kindly requests that recruiters not contact employees/hiring managers directly in an attempt to solicit business and present candidates. Please note that failure to comply with this request will be a factor in determining a professional relationship with our organization. Submission of unsolicited resumes prior to an agreement set in place between the Human Resources Department and the recruiting agency will not create any implied obligation. Inquiries on developing a recruiting relationship with us, may be directed to: [email protected].

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