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Senior Manager, Medical Affairs Operations - Neurology / Ophthalmology

Annexonbioscience

San Francisco Bay Area (Annexon HQ) Remote permanent

Posted: October 31, 2025

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Job Description

Company:

At Annexon Biosciences we are a biopharmaceutical company advancing a late-stage clinical platform of novel therapies for people living with devastating classical complement-mediated neuroinflammatory diseases of the body, brain, and eye. Our novel scientific approach targets upstream C1q to block the classical complement inflammatory cascade before it starts, and its therapeutic candidates are designed to provide meaningful benefits across multiple autoimmune, neurodegenerative and ophthalmic diseases. With proof-of concept data in Guillain-Barré syndrome, Huntington’s disease and geographic atrophy, we are rigorously advancing our mid-to late-stage clinical trials to bring new potential treatments to patients as quickly as possible. At Annexon, you’ll be part of a team committed to making an impact together.

For more information on Annexon and our pipeline, check out our site Annexon Biosciences & Annexon Pipeline. We trade on Nasdaq under the ticker symbol ANNX and are headquartered in Brisbane, CA.

We're seeking exceptional talent from all backgrounds to fuel our growth. At Annexon, we're building a diverse, equitable, and inclusive workplace. We value unique perspectives and unconventional paths. If you're the best candidate for the job, even if you don't perfectly fit the traditional mold, we encourage you to apply. Learn more about our commitment to diversity, equity, inclusion, and our company culture!

Position:

The Senior Manager of Medical Affairs (MA) Operations - Neurology / Ophthalmology will be integral to supporting the neurology and ophthalmology Medical Affairs Teams by managing and executing key projects within the neurology and ophthalmology therapeutic areas (TAs). This role includes coordinating with external vendors, planning meetings, and ensuring compliance with contract processes. This individual will be a key member of the leadership team overseeing the entire portfolio of Annexon Medical Affairs activities and pipeline, requiring a deep understanding of pharmaceutical operations and strategic planning.

Responsibilities include:

• Collaborate with MA TA VPs, MSL Team Leads, and Medical Director(s) to plan and execute projects aligned with therapeutic area objectives.

• Manage relationships with meeting planning/logistics vendors, MLR program vendors, medical education agencies, and CRM agencies, to support MA activities in neurology and ophthalmology.

• Support planning and execution of onsite and offsite meetings for internal and external stakeholders, including departmental All Hands meetings, field medical meetings, advisory boards, and congress-based activities.

• Operationalize congress activities and partner with legal on contracting for various activities such as society sponsorships, exhibit planning, and group/1:1 KOL engagements.

• Liaise with the Contracts Team to ensure timely submission and full execution of all contracts. Implement processes for submitting and tracking consultant contracts to ensure compliance.

• Support compliance with Annexon policies, including but not limited to submission of advisory board approval requests to Legal.

• Work with the VPs of MA to develop the annual tactical plan and budget. Track budget performance quarterly.

Education, Experience, and Skills:

Required:

• Minimum of 5 years' experience in a functional biopharma operations role (e.g., medical affairs, commercial, R&D, other) managing activities with internal and external stakeholders.

• Excellent verbal and written communication skills to represent Annexon MA with key stakeholders.

• Comprehensive knowledge of pharmaceutical product development, cross-functional roles, and key external stakeholders.

• Expertise in project management, resource planning/management, and common digital platforms in fast-paced and dynamic settings to achieve results based on key performance indicators.

• Self-driven, with demonstrated ability to make informed decisions and solve problems with sound judgment.

• Cross-functional collaboration expertise.

• Bachelor's degree is preferred.

Salary Range: $156,000 - $173,500

Location: Annexon Biosciences is located in Brisbane, California and preference is given to candidates in the San Francisco Bay Area.

Benefits:

• A stimulating and rewarding workplace includes flexible work schedules, remote opportunities and the ability to achieve a work-life balance.

• Shuttle service from BART, CalTrain and the Ferry.

• Annexon offers a competitive base salary and equity participation, employee stock purchase plan, as well as a comprehensive health benefit package that includes medical, dental, vision, 401(k), flexible spending plans, and other benefits.

Annexon Biosciences is an Equal Opportunity Employer, and we prohibit discrimination or harassment of any kind. We are committed to fostering an environment where ALL people are welcome and supported. We cultivate a culture of inclusion for all employees that respects their individual strengths, views, and experiences. We believe that our differences enable us to be a better team – one that makes better decisions, drives innovation, and delivers better business results. Creativity and innovation flourish in an environment of openness, inclusion, and mutual respect.

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