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Senior Manager, LTC & Digital Sales Effectiveness

Axsometherapeutics

New York, NY (NYC Headquarters) Remote permanent

Posted: January 30, 2026

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Quick Summary

Senior Manager, LTC & Digital Sales Effectiveness, New York, NY, requires a strong background in sales and marketing, with expertise in digital sales strategies and a proven track record of driving revenue growth.

Job Description

Axsome Therapeutics is a biopharmaceutical company leading a new era in the treatment of central nervous system (CNS) conditions. We deliver scientific breakthroughs by identifying critical gaps in care and develop differentiated products with a focus on novel mechanisms of action that enable meaningful advancements in patient outcomes. Our industry-leading neuroscience portfolio includes FDA-approved treatments for major depressive disorder, excessive daytime sleepiness associated with narcolepsy and obstructive sleep apnea, and migraine, and multiple late-stage development programs addressing a broad range of serious neurological and psychiatric conditions that impact over 150 million people in the United States. Together, we are on a mission to solve some of the brain’s biggest problems so patients and their loved ones can flourish. For more information, please visit us at www.axsome.com and follow us on LinkedIn and X.

About This Role:

Axsome Therapeutics is seeking a Senior Manager, LTC/DSAM Field Effectiveness to build and lead the operational infrastructure for our new Long-Term Care (LTC) sales force targeting demand originating from facility-based settings. This role requires establishing entirely new analytical capabilities around facility-level data, transitioning from traditional physician-focused operations to facility-based commercial models. The position demands technical expertise in data integration, advanced analytics, incentive compensation and operational system design to support PointClickCare data onboarding. In addition this role will support an expanded Digital sales team on reporting, targeting to support geos that have solo coverage and incentive compensation. This role reports directly to the Director, Field Effectiveness.

This role is based at Axsome’s HQ in New York City with an on-site requirement of at least three days per week. We are unable to consider candidates who are looking for fully remote roles.

Job Responsibilities and Duties include, but are not limited to, the following:

• Lead PointClickCare data integration project to establish facility-based analytics infrastructure, including designing data ingestion pipelines, normalizing facility/resident data structures, and establishing regular refresh cadences

• Build facility-level targeting and segmentation models incorporating census data, prescribing patterns, payer mix, and formulary status

• Develop facility profiling algorithms that identify high-opportunity targets based on disease prevalence, current treatment patterns, and competitive dynamics

• Build comprehensive LTC analytics infrastructure linking LTC rep activity to facility adoption. Implement cohort analysis frameworks to track facility product productivity over time

• Manage ongoing reporting, alignment, call planning, and IC design and admin for the LTC and Digital sales force

• Redesign DSAM targeting to optimize reach and frequency based on whether the hcp is currently covered by dual or single in person sales reps

• Create dashboards and reporting tools showing LTC sales force performance versus traditional team across key metrics, facility-level trends, rep performance, and formulary tracking

• Create ad hoc analyses to identify field execution opportunities based on CRM engagement data and secondary data sources (PCC, Symphony).

• Support LTC and DSAM Sales leadership in the organization and coordination of National Sales Meetings and POA planning sessions

• Collaborate with broader Commercial Operations team on cross-team optimization initiatives

Requirements / Qualifications

• BS/MS/PhD in Engineering, Physics, Applied Physics, Statistics, Computer Science, or related quantitative field strongly preferred

• A minimum of 6 years of sales operations experience in the pharmaceutical or biotech industry (which may include work as a consultant or supplier to the industry)

• Expert-level SQL skills for complex queries, joins, and data manipulation. Advanced proficiency in Python (pandas, numpy) or R for data analysis and automation

• Advanced Excel capabilities including VBA/macros, Power Query, Power Pivot, and complex formula design

• Ability to work on site Monday, Tuesday & Thursday. We are unable to consider candidates who are looking for fully remote roles

Experience, Knowledge and Skills

• Excellent written and verbal communication skills with ability to translate complex technical concepts into clear business insights for all organizational levels

• Experience in Sales Force Design, Alignment, Targeting, Call Planning, and Incentive Compensation

• Experience in omnichannel planning and supporting Veeva CRM applications

Salary and Benefits:

The anticipated salary range for this role is $140,000 - $160,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

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