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Senior IT Business Systems Analyst, SAP Supply Chain

Vaxcyte

San Carlos, California, United States (San Carlos, California) permanent

Posted: January 27, 2026

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Quick Summary

Join our team as a Senior IT Business Systems Analyst to help design and implement business processes and systems to improve efficiency and productivity.

Job Description

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

Vaxcyte is undergoing a major ERP transformation, moving to SAP S/4HANA to support its rapid growth and upcoming transition to Commercial Operations. The IT SAP Supply Chain Senior Business Systems Analyst (BSA) will play a critical role in bridging Supply Chain and IT, ensuring successful implementation, stabilization, and ongoing optimization of SAP S/4HANA Supply Chain capabilities. This position requires strong functional expertise in SAP Supply Chain functionalities, deep understanding of contract manufacturing processes, and experience in complex ERP implementation projects.

Essential Functions:

• Support the implementation and stabilization of SAP S/4HANA Supply Chain modules in a regulated environment.

• Collaborate with Supply Chain, Manufacturing, Quality, and IT teams to design future-state processes aligned with Vaxcyte's CDMO business model.

• Assist in data mapping, migration, cleansing, and validation during cutover and post-go-live activities.

• In-depth knowledge of SAP S/4HANA systems and integration techniques with third-party planning systems.

• Expertise with agile methodology, global deployments, and data migration planning.

• Experience working in GxP validated and SOX regulated systems.

• Configure and maintain SAP Supply Chain modules including Materials Management (MM), Master Data, Subcontracting & External Processing, Batch Management, and Forecast Consumption & Demand Planning.

• Assist with the integration points with FI (Financial Accounting) & CO (Controlling)

• Support end-to-end planning flows from demand through manufacturing and supply execution.

• Excellent verbal and written communication skills, with the ability to effectively communicate complex technical concepts to non-technical stakeholders.

• Work closely with Supply Chain stakeholders (Planning, Procurement, Finance) to capture requirements.

• Translate business needs into functional specifications for SAP configuration.

• Help develop and document business process flows.

• Support complex planning scenarios where capacity, lead times, and execution are controlled by external CDMO partners.

• Develop and execute test plans for SAP Supply Planning processes.

• Support User Acceptance Testing (UAT) and resolve issues promptly.

• Ensure validation readiness and maintain audit trail expectations in compliance with regulatory requirements.

• Training & Change Management

• Create training materials and deliver sessions for Supply Chain users.

• Provide ongoing support post go-live.

• Ensure compliance with GxP standards and Life Sciences industry requirements.

Requirements:

• Minimum of 7 years of experience as a BSA with SAP Supply Chain modules.

• Bachelor's degree in Supply Chain, Operations, Information Systems, or related field

• Strong analytical and problem-solving skills, with the ability to independently diagnose and resolve SAP supply chain issues in complex CDMO-based manufacturing environments.

• Experience in identifying and managing project risks, with a proactive approach to mitigation.

• Familiarity with change management principles and techniques to facilitate smooth transitions and adoption of new systems.

• Hands-on experience with SAP S/4HANA Supply Chain (implementation or migration projects preferred) and Fiori applications.

• Proven experience supporting SAP-based contract manufacturing or CDMO operating models.

• Experience developing and mapping business process flows using Visio or similar tool.

• Strong understanding of Supply Chain processes and ERP implementation best practices.

• Excellent communication and stakeholder management skills.

• Solid experience managing SAP master data relevant to supply planning (materials, vendors, sourcing, BOMs).

• Other combinations of education and/or experience may be considered.

Reports to: Director, IT Supply Chain Systems

Location: San Carlos, CA

Compensation:

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Salary Range: $163,000 - $190,000 (SF Bay Area). Salary ranges for non-California locations may vary.

Relocation:

This role is eligible for relocation assistance.
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

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