Senior Information Security Engineer

At Adaptive, we’re Powering the Age of Immune Medicine. Our goal is to harness the power of the adaptive immune system to transform the way diseases are diagnosed and treated.

As an Adapter, you’ll have the opportunity to make a difference in people’s lives. With Adaptive, you’ll create a career highlight through collaboration with bright, curious colleagues working at the apex of innovation and application.

It’s time for your next chapter. Discover your story with Adaptive.

Position Overview

The Senior Information Security Engineer is responsible for designing, building, and owning the security systems and controls across Adaptive’s environment. This role focuses on developing scalable, effective solutions that reduce risk and improve the organization’s ability to prevent, detect, and respond to threats.

This role is expected to build and own security capabilities end-to-end from initial design through production operation and continuous improvement.

As part of the Information Security team, this role partners closely with Security Operations and is responsible for building and improving the systems they rely on. The ideal candidate is a hands-on engineer who can operate across domains, work with imperfect data, and drive practical improvements in a dynamic environment.

Key Responsibilities and Essential Functions

Security Engineering & Control Implementation

• Design, implement, and improve security controls across cloud, endpoint, and application environments

• Evaluate and integrate security tools and technologies to improve coverage and effectiveness

• Identify gaps in existing controls and drive remediation

• Own control effectiveness and continuously improve based on real-world outcomes

Detection & Telemetry

• Own and improve detection logic across key security systems in partnership with Security Operations

• Co-own detection signal quality with Security Operations, continuously refining signal, reducing noise, and eliminating blind spots

• Design and maintain security telemetry pipelines, including log ingestion, normalization, and data quality

• Improve logging and visibility across systems to enable effective detection and response

Secure Development & System Integration

• Partner with engineering teams to integrate security into the software development lifecycle

• Define and implement security requirements for applications, infrastructure, and CI/CD pipelines

• Support secure design and architecture decisions through practical implementation

Automation & Tooling

• Build automation and integrations to improve the scalability and efficiency of security operations

• Leverage scripting and APIs to reduce manual work and improve consistency

• Develop systems that enrich, correlate, and operationalize security data

Continuous Improvement

• Use insights from incidents, vulnerabilities, and operational metrics to improve security systems and controls

• Contribute to evolving security standards, engineering practices, and technical direction

Position Requirements

• Bachelor’s degree and 7+ years of relevant experience, or equivalent practical experience

• Hands-on experience building and implementing security controls or systems in cloud, SaaS, or modern infrastructure environments

• Experience working with structured or semi-structured data and building systems that process and analyze that data

• Experience in one or more of the following areas: detection engineering, security telemetry/logging, vulnerability management, endpoint security, or application security

• Strong scripting or programming skills (e.g., Python), with experience building automation or data processing workflows

• Experience working with APIs and integrating systems

• Experience debugging and improving complex systems in production environments

• Solid understanding of security fundamentals (authentication, authorization, networking, common attack patterns)

• Ability to work cross-functionally and drive technical solutions in a dynamic environment

Preferred Qualifications

• Experience designing or implementing SIEM or logging pipelines

• Experience improving vulnerability management programs beyond basic scanning

• Familiarity with cloud environments and modern infrastructure patterns

• Experience in regulated environments, particularly medical devices or clinical laboratory (e.g., HIPAA, SOC 2, ISO 27001)

Working Conditions

• Administrative work in a home/office environment.

• Regular weekday work hours, with occasional weekend/after-hours planned or unplanned work as needed.

#LI-Remote

Compensation

Salary Range: $128,700 - $193,100

Other compensation elements include:

• equity grant

• bonus eligible

ALERT: Malicious groups posing as Adaptive employees have recently used fraudulent email aliases to extend employment offers, provide fake documents, and request sensitive personal and financial information. Legitimate Adaptive employment opportunities are initiated through our careers page and extended after multiple interviews with verified employees. Adaptive does not ask new hires to purchase anything out-of-pocket, including home office supplies and equipment.

Interested in this position, but don’t meet all the requirements? Adaptive is committed to building diverse, equitable, and inclusive teams across our organization. Please consider applying even if your experience doesn’t match all the qualifications; you may be the exact candidate we’re searching for!

Adaptive is not currently sponsoring candidates requiring work authorization support for this position.

Adaptive’s posted compensation information includes a base salary (or hourly rate) range and summary of other available total compensation. The base salary range represents a minimum-to-maximum salary (or hourly rate) available to candidates upon extension of offer. Base salary is thoughtfully considered upon offer and is determined through multiple evaluation checks throughout the interview process, including: a candidate’s ability to meet minimum qualifications (skills/experience/education), a candidate’s ability to thoughtfully address preferred qualifications, current market conditions, and internal pay equity. Listed base salary is exclusive of bonus, commission, equity, differential pay, benefits, and other incentives.

Adaptive's benefits at-a-glance.

Adaptive Biotechnologies is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against based on disability. Please refer the “Know Your Rights: Workplace Discrimination is Illegal” Poster for more information. If you’d like to view a copy of the company’s affirmative action plan or policy statement, please email [email protected].

If you have a disability and you believe you need a reasonable accommodation to search for a job opening or to submit an online application, please e-mail [email protected]. This email is created exclusively to assist disabled job seekers whose disability prevents them from being able to apply online. Only messages left for this purpose will be returned. Messages left for other purposes, such as following up on an application or technical issues not related to a disability, will not receive a response.

NOTE TO EMPLOYMENT AGENCIES: Adaptive Biotechnologies values our relationships with our Recruitment Partners and will only accept resumes from those partners who have active agreements with Adaptive. Adaptive Biotechnologies is not responsible for any fees related to resumes that are unsolicited or are received by any employee of Adaptive Biotechnologies who is not a member of the Human Resources team.