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Senior Director, IT SAP Systems

Vaxcyte

San Carlos, California, United States (San Carlos, California) permanent

Posted: January 14, 2026

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Quick Summary

Join our team to protect humankind from bacterial diseases and contribute to the development of high-fidelity vaccines.

Job Description

Join our Mission to Protect Humankind!

Vaxcyte is a clinical-stage vaccine innovation company engineering high-fidelity vaccines to protect humankind from the consequences of bacterial diseases, which have serious and costly health consequences when left unchecked. Working to eradicate or treat bacterial infections such as invasive pneumococcal disease, Group A Strep, and Shigella is just the beginning. Our path to success is clear and well-defined, and Vaxcyte is set up to go the distance.

WHAT we do is every bit as important as HOW we do it! Our work together is guided by four enduring core values:

*RETHINK CONVENTION: We bring creative and intellectual diversity to every facet of the work we do in order to innovate and re-innovate the way vaccines are delivered.

*AIM HIGH: We embody our collectively audacious goal to courageously make the most complex biologics ever attempted to protect humankind.

*LEAD WITH HEART: Everyone leads at Vaxcyte with a kindness-first, inclusive approach to collaboration and vigorous debate that advances our business objectives.

*MODEL EXCELLENCE: The magnitude of our challenge requires our shared commitment to demonstrating integrity, accountability, equality and clarity across communications and decision making.

Summary:

The Senior Director of IT SAP Systems is a key leadership role responsible for the successful planning, delivery and ongoing management of Vaxcyte’s SAP and Advanced Planning & Scheduling (APS) initiatives. This individual will oversee and manage the implementation of our upcoming SAP Enterprise Resource Planning (ERP) and OMP Advanced Planning Systems (APS). This position requires a strategic thinker with a high level of expertise in SAP and APS systems. They will provide team leadership to ensure that business goals and objectives are met efficiently and effectively. This is a collaborative hands-on role working closely with business partners and subject matter experts from supply chain, finance and other business teams to deliver ERP/APS solutions that will support our growth through vaccine commercialization and beyond. The position reports to the Senior Vice President, IT & Facilities at Vaxcyte’s San Carlos, California headquarters.

Essential Functions:

• Lead and execute SAP and OMP implementations and subsequent projects ensuring alignment with organizational objectives and strategic goals.

• Deep experience collaborating with stakeholders to understand their requirements, manage expectations, and provide regular project updates.

• Vendor collaboration, budget planning, preparing for and facilitating steering committee meetings.

• Identify, assess, and mitigate project risks to minimize potential impact on project outcomes.

• Implement change management processes for SAP and APS to ensure smooth transitions and adoption of new systems and processes. In addition, develop support for tracking GxP and SOX related changes.

• Monitor project performance using appropriate systems, tools, and techniques, and implement corrective actions as needed.

• Create and curate program standards including tools, deliverables and document management.

• Promote a culture of continuous improvement by identifying areas for enhancement and implementing best practices in SAP and APS through initial implementation and lifecycle management.

• Lead a cross functional team from the business, IT, consultants, contract manufacturer resources, and other professionals to achieve high performance and project success.

Requirements:

• Bachelor’s degree in Information Technology, Business Administration, or a related field. A master’s degree or relevant certifications (e.g., PMP, SAP certification) is desired.

• At least 14 years of experience in program/project management, with multiple SAP and APS system implementations. Other combinations of education and/or experience may be considered.

• Experience leading large and complex initiatives, including development of detailed timelines, milestone creation, and resource requirements to ensure timeline execution and delivery.

• In-depth knowledge of SAP systems, including SAP S/4HANA and integration techniques.

• Experience implementing APS systems (OMP experience is desired).

• Experience delivering large scale SAP projects.

• Expertise with agile methodology, global deployments and data migration planning.

• Leadership: Strong leadership and team management skills, with the ability to motivate and guide cross-functional teams.

• Excellent verbal and written communication skills, with the ability to effectively communicate complex technical concepts to non-technical stakeholders.

• Strong background implementing and maintaining GxP validated and SOX regulated systems

• Strong analytical and problem-solving skills, with the ability to identify issues and implement effective solutions.

• Experience in identifying and managing project risks, with a proactive approach to mitigation.

• Proficiency in change management principles and techniques to facilitate smooth transitions and adoption of new systems.

• Experience with biotech/pharma companies both pre and post commercialization.

Reports to: Senior Vice President, Information Technology & Facilities

Location: San Carlos, CA

Compensation:

The compensation package will be competitive and includes comprehensive benefits and an equity component.

Salary Range: $270,000 - $316,000 (SF Bay Area). Salary ranges for non-California locations may vary.

Relocation:

This role is eligible for relocation assistance.
We are an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or veteran status.

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