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Senior Director, Clinical Operations Products & Platforms

AstraZeneca

US - Durham - NC permanent

Posted: March 18, 2026

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Job Description

Are you ready to lead the charge in transforming clinical operations through innovative data strategies? As the Senior Director of Clinical Operations Products and Platforms, you'll define and guide the strategic direction of data solutions and infrastructures. You will ensure they meet protocols and include input from collaborators. This pivotal role is your chance to drive strategic platform delivery and make a significant impact in the world of Clinical Operations.

Accountabilities 

• Develop a comprehensive multi-year strategy for Clinical Operations Data Products and Platforms, ensuring delivery through capability sizing, skill profiling, supplier models, technology platforms, and cross-capability engagement. 
 
• Leverage domain and technical expertise to supervise and guide teams in transforming unstructured, complex business challenges into data designs, solutions, and services aimed at optimizing trial design and accelerating clinical trial operations. 
 
• Build and sustain effective relationships with senior stakeholders to maximize the utilization and value of information resources and services across data product roadmaps. 
 
• Ensure all product deliverables within the domain clearly and objectively communicate results, including associated risks, uncertainties, and limitations. 
 
• Advocate for continuous knowledge development and awareness of trends, best practices, and emerging advancements in the data landscape to shape functional practices and strategies. 
 
• Collaborate with leaders in Clinical Operations across Therapy Areas, Enterprise AI, Clinical Development, and IT organizations to ensure platforms provide strategic data support aligned with Clinical Operations' ambitions. 
 
• Lead multiple data product directors across global locations and partner with engineering teams to deliver features with clarity, adhering to agreed roadmaps and priority initiative planning. 
 
• Drive best practices and cross-functional collaboration within the AstraZeneca Data and AI community to deliver measurable value. 
 
• Manage and maintain accountability for partnerships with third-party vendors and outsourced partners. 
 
• Actively participate in the functional Leadership Team to influence and shape functional strategy. 

Essential Skills/Experience
- Undergraduate degree in Computer Science, Data Management, or a related discipline (e.g., R&D, Finance, HR)
- Equivalent years of experience in a data product/platform role
- Extensive experience in data analysis or business roles aligned with data and information management
- Strong domain data understanding, including the structure, provenance, and meaning of source data (e.g., CTMS, eTMF)
- Familiarity with business processes related to data generation and consumption
- Proven leadership experience in delivering data product management, visioning, and strategy activities
- Expertise in leading data strategy within large, complex organizations
- Experience working in multi-skilled, multi-location data teams adhering to agile principles
- Awareness of end-to-end processes in building and supporting data solutions
- Skilled in applying risk-based methodologies to data and information management
- Proven experience in navigating complex global organizations

Desirable Skills/Experience
- Experience in life sciences and healthcare

When we put unexpected teams in the same room, we unleash bold thinking with the power to encourage life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our outstanding and ambitious world.

At AstraZeneca, curiosity meets courage as we explore the potential of science to tackle some of the world's most complex diseases. Our inclusive environment encourages collaboration among a diverse set of minds spanning academia to biotech. By integrating digital innovation with scientific expertise, we are poised to redefine healthcare. Here, every voice matters as we strive for breakthroughs that can transform lives globally. 

Ready to make a difference? Apply now to join our team of pioneers!

Date Posted

18-Mar-2026

Closing Date

25-Mar-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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