Senior Clinical Programmer I

Job Title: Senior Clinical Programmer I
Location: Durham, Emperor Blvd
 

At AstraZeneca, we put patients first and strive to meet their unmet needs worldwide. Working here means being entrepreneurial, thinking big and working together to make the impossible a reality. If you are swift to action, confident to lead, willing to collaborate, and curious about what science can do, then you’re our kind of person.
 

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week. Our head office is purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects. 

Our dedication to sustainability is also central to our culture and part of what makes AstraZeneca a great place to work. We know the health of people, the planet and our business are interconnected which is why we’re taking ambitious action to tackle some of the biggest challenges of our time, from climate change to access to healthcare and disease prevention. 

Introduction to Role:
 

The Senior Clinical Programmer I is primarily responsible for activities related to programming, dashboard development and validation of data cleaning and review listings and sophisticated programs for ongoing clinical studies. This position requires high technical skills and adequate industry knowledge to independently perform programming tasks while using judgement about seeking mentorship in complex situations. Senior Clinical Programmer will contribute to multi-functional initiatives with High complexity.
 

Accountabilities:

• Responsibilities include (but not limited to) design, development, implementation, and validation of sophisticated programs built in SAS/Python/R or dashboard applications such as PowerBI/Spotfire.
• Works towards the design, development, implementation, and validation of PowerBI dashboard applications
• Programs independently with efficiency and quality to process, analyse and report clinical trial data ready for review by clinical study teams
• Contribute to design, develop and implement High complex projects or initiatives that are part of clinical programming roadmap
• Contribute to defining and building vital processes and tools to perform clinical programming activities for both global and study level analytical solutions
• Contributes to development of guidelines that enhances quality, efficiency, timelines and effectiveness within the function
• Provide technical expertise, cross training and support as required to ensure the availability and performance of developed reports and dashboards for both external and internal users
• Lead all aspects of completion of documentation associated with programming tasks to ensure activities and processes performed are conducted per standard operating procedures, guidelines and protocols
• Ensures high quality is built into own work and quality delivered by other programmers
• Identifies and communicates risk within assigned studies and/or projects
• Collaborates with various teams including data management, development operations, clinical, biometrics and other relevant multi-functional teams supporting clinical trials to deliver end user reporting needs
• Develop and maintain data visualization tools including requirements gathering, data provisioning and building dashboards as needed
• Create and maintain catalogue of reports to aid data cleaning and reporting activities
• Provide technical expertise, cross training and support as required to ensure the availability and performance of developed reports and dashboards for both external and internal users
• Oversee completion of documentation associated with programming tasks to ensure activities and processes performed are conducted per standard operating procedures, guidelines and protocols

Essential Skills/Experience:

• Bachelor’s Degree with a minimum of 5 years of experience in a professional environment.

• Accomplished programming skills in SAS/Python/R/SQL/ SQL/Power BI/ SpotFire or other dashboard technologies
• Intermediate knowledge of clinical development process
• Good knowledge of industry standards
• Ability to influence relevant partners.
• Excellent analytical and critical thinking skills, writing, communication skills, and ability to work within a multi-functional team
• Ability to work in a distributed team environment.
• Technical expertise with data capture, data models, data mining, and visualization techniques.
• Prior Experience and understanding of EDC systems like Medidata Rave / Inform / Veeva and Data Platforms like Saama/ Entimice, SAS LSAF etc
 

Desirable Skills/Experience:

• Bachelor’s/Master’s degree or equivalent in computer science, life science or statistics

• Excellent collaborative skills and the ability to manage complexity and change in a dynamic environment
• Broad knowledge of FDA regulations and GCP/ICH guidelines as related to clinical programming processes.
• Experience in producing analytical dashboards with Power BI, Spotfire or other Business Intelligence tools.
• Knowledge on MicroStrategy

Where can I find out more?

• Our Social Media, Follow AstraZeneca on LinkedIn https://www.linkedin.com/company/1603/
• Follow AstraZeneca on Facebook https://www.facebook.com/astrazenecacareers/
• Follow AstraZeneca on Instagram https://www.instagram.com/astrazeneca_careers/?hl=en
• Our US Footprint: Powering Scientific Innovation - YouTube

Are you interested in working at AZ, apply today!

AstraZeneca is an equal opportunity employer that is committed to diversity and inclusion and providing a workplace that is free from discrimination. AstraZeneca is committed to accommodating persons with disabilities. Such accommodation is available on request in respect of all aspects of the recruitment, assessment and selection process and may be requested by emailing [email protected].

Date Posted

09-Mar-2026

Closing Date

19-Mar-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.