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Senior Backend Software Engineer - Integrations

Arine

Remote (United States of America) (Arine - Remote) Remote permanent

Posted: February 19, 2026

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Quick Summary

We are looking for a Senior Backend Software Engineer with expertise in integrating complex data pipelines. Key skills include experience with machine learning, AI, and data science, and a strong background in software development. This is a challenging role that requires a deep understanding of the healthcare industry and a passion for solving real-world problems.

Job Description

Based in San Francisco, Arine is a rapidly growing healthcare technology and clinical services company with a mission to ensure individuals receive the safest and most effective treatments for their unique and evolving healthcare needs.

Frequently, medications cause more harm than good. Incorrect drugs and doses costs the US healthcare system over $528 billion in waste, avoidable harm, and hospitalizations each year. Arine is redefining what excellent healthcare looks like by solving these issues through our software platform (SaaS). We combine cutting edge data science, machine learning, AI, and deep clinical expertise to introduce a patient-centric view to medication management, and develop and deliver personalized care plans on a massive scale for patients and their care teams.

Arine is committed to improving the lives and health of complex patients that have an outsized impact on healthcare costs and have traditionally been difficult to identify and address. These patients face numerous challenges including complicated prescribing issues across multiple medications and providers, medication challenges with many chronic diseases, and patient issues with access to care. Backed by leading healthcare investors and collaborating with top healthcare organizations and providers, we deliver recommendations and facilitate clinical interventions that lead to significant, measurable health improvements for patients and cost savings for customers.

Why is Arine a Great Place to Work?:

Outstanding Team and Culture - Our shared mission unites and motivates us to do our best work. We have a relentless passion and commitment to the innovation required to be the market leader in medication intelligence.

Making a Proven Difference in Healthcare - We are saving patient lives, and enabling individuals to experience improved health outcomes, including significant reductions in hospitalizations and cost of care.

Market Opportunity - Arine is backed by leading healthcare investors and was founded to tackle one of the largest healthcare problems today. Non-optimized medications therapies which cost the US 275,000 lives and $528 billion annually.

Dramatic Growth - Arine is managing more than 18 million lives across prominent health plans after only 4 years in the market, and was ranked 236 on the 2024 Inc. 5000 list and was named the 5th fastest-growing company in the AI category.

The Role:

As a Senior Backend Software Engineer at Arine, you'll build and maintain the core APIs and data processing systems that power our healthcare platform. You'll work with Python, AWS technologies, and both SQL and NoSQL databases to develop scalable solutions that integrate with healthcare systems and securely process patient data.

What You'll Be Doing:

• Architect and implement production-grade Python applications (REST APIs, CLIs, libraries, and scripts)

• Design and build integrations with Electronic Health Record (EHR) systems (Epic, Oracle Health/Cerner), handling HL7/FHIR data formats

• Lead development of new features using AWS stack

• Troubleshoot and resolve production issues in mission-critical healthcare infrastructure

• Establish testing standards and write comprehensive unit/integration tests

• Drive technical improvements: refactor legacy code, optimize performance, reduce technical debt

• Mentor junior engineers and contribute to technical architecture decisions

• Collaborate cross-functionally with Frontend Engineers, Data Engineers, and Clinical Operations teams

Our Ideal Candidate Possesses:

Technical Expertise:

• 5+ years of Python development with proven ability to build and deploy production APIs, CLIs, libraries, and scripts

• Advanced proficiency in AWS Services: Lambda, DynamoDB, S3, RDS, CloudFormation, SQS, SNS, EventBridge, Kinesis

• Experience with container orchestration (EKS, ECS, or Kubernetes)

• Experience with healthcare data, EHR systems (Epic/Cerner), or HL7/FHIR standards

• Experience in architecting and scaling multi-component distributed systems

• Deep understanding of:

• Synchronous vs. asynchronous design patterns and when to use each

• SQL (PostgreSQL) vs. NoSQL (DynamoDB) database selection, design, and optimization

• REST API design principles

• Experience with Test-Driven Development (TDD), unit/integration testing, and mocking strategies

• Experience with Git/GitHub workflows, branching strategies, and code review processes

Leadership & Collaboration:

• Experience owning complex projects end-to-end: gathering requirements, designing solutions, implementing, and delivering

• Strong communication skills to translate technical concepts for stakeholders and collaborate effectively

• Experience mentoring junior engineers and contributing to technical decision-making

• Experience working in fast-paced environments with the ability to adapt to changing priorities

• Proven ability to deliver high-quality work against deadlines

• Ability to work independently and drive initiatives forward while being a collaborative team player

Nice-to-Haves:

• Experience with AI-assisted coding tools (e.g., Claude, Cursor, GitHub Copilot) to accelerate development while maintaining code quality standards

• Experience with CI/CD tools: Jenkins, Docker, Kubernetes, GitHub Actions

• Experience with event-driven and serverless architectures

• Experience with database optimization: query tuning, index design, aggregation strategies

• Experience with monitoring/observability tools (CloudWatch, X-Ray, Datadog, etc.)

Travel and Other Information:

• For candidates local to the San Francisco Bay Area, the ability to commute to our office on Market Street in San Francisco at least 2-3 days/week

• Ability to travel to Arine's San Francisco office at least twice per year

Remote Work Requirements:

• An established private work area that ensures information privacy

• A stable high-speed internet connection for remote work

• This role is remote, but you will be required to come to on-site meetings multiple times per year. This may be in the interview process, onboarding, and team meetings

Perks:

Joining Arine offers you a dynamic role and the opportunity to contribute to the company's growth and shape its future. You'll have unparalleled learning and growth prospects, collaborating closely with experienced Clinicians, Engineers, Software Architects, and Digital Health Entrepreneurs.

The posted range represents the expected salary for this position and does not include any other potential components of the compensation package, benefits, and perks. Ultimately, the final pay decision will consider factors such as your experience, job level, location, and other relevant job-related criteria. The salary range for this position is: $150,000-170,000/year.

Job Requirements:

• Ability to pass a background check

• Must live in and be eligible to work in the United States

Information Security Roles and Responsibilities:

All staff at Arine are expected to be part of its Information Security Management Program and undergo periodic training on Information Security Awareness and HIPAA guidelines. Each user is responsible to maintain a secure working environment and follow all policies and procedures. Upon hire, each person is assigned and must complete trainings before access is granted for their specific role within Arine.

Arine is an equal opportunity employer. We are committed to creating a diverse and inclusive workplace where all employees are treated with fairness and respect. We do not discriminate on the basis of race, ethnicity, color, religion, gender, sexual orientation, age, disability, or any other legally protected status. Our hiring decisions and employment practices are based solely on qualifications, merit, and business needs. We encourage individuals from all backgrounds to apply and join us in our mission.

Check our website at https://www.arine.io. This is a unique opportunity to join a growing start-up revolutionizing the healthcare industry!

Job Offers: Arine uses the arine.io domain and email addresses for all official communications. If you received communication from any other domain, please consider it spam.

Note to Recruitment Agencies: We appreciate your interest in finding talent for Arine, but please be advised that we do not accept unsolicited resumes from recruitment agencies. All resumes submitted to Arine without a prior written agreement in place will be considered property of Arine, and no fee will be paid in the event of a hire. Thank you for your understanding.

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