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Senior Accountant

Lexeotx

New York, New York Remote permanent

Posted: March 28, 2026

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Quick Summary

We are seeking a highly motivated Senior Accountant to join our growing team. As Senior Accountant, you will be responsible for preparer of most accounting workpapers and support, reporting to the Associate Director/Director of Accounting and working closely with the AP Manager.

Job Description

Role Summary

We are seeking a highly motivated Senior Accountant to join our growing team. As Senior Accountant, you will be the primary preparer of most accounting workpapers and support, reporting to the Associate Director/Director of Accounting and SEC Reporting and working closely with the AP Manager. This is an exciting opportunity to contribute to the advancement of cutting-edge medical treatments and shape the future of healthcare.

We welcome applications from candidates located across the Northeast and Mid-Atlantic.


Primary Responsibilities:
• Participate in the monthly and annual accounting closing processes and contribute to producing accurate and timely financial statements

• Prepare all recurring monthly journal entries

• Maintain all balance sheet reconciliations and update monthly to ensure accurate reporting

• Provide detailed fluctuation analysis for month end closing

• Maintain effective internal controls and prepare annual internal control process narratives and key control analysis

• Assist AP Manager in proper coding of invoices

• Ensure financial records are maintained in compliance with GAAP

• Support financial statement audits and reports

• Collaboration with operational personnel on financial and operational matters

• Special projects and other assignments as required


Required Skills and Qualifications:
• BA/BS degree in Accounting or related field

• 3-5 years of experience in an Accounting role

• Ability to work effectively with all levels of an organization

• Strong analytical skills with a high level of accuracy and attention to detail

• Ability to manage competing priorities and deadlines and strong problem-solving skills

• Strong written and verbal communication

• Intermediate or Advanced aptitude in Excel is required

• CPA or equivalent (or on-track) preferred

• Experience with a Big 4 or national firm, SEC registered company and/or Biotech company is preferred

• Familiarity with NetSuite and FloQast a plus

• Ability to travel to HQ quarterly


About Lexeo

Lexeo Therapeutics is a clinical-stage genetic medicine company headquartered in New York City, pioneering cardiac genetic medicine candidates to treat the root causes of inherited cardiovascular diseases. Our lead program, LX2006, targets cardiomyopathy associated with Friedreich’s Ataxia and anchors a broader pipeline addressing genetically defined conditions such as hypertrophic and arrhythmogenic cardiomyopathies. Backed by a strong financial foundation, Lexeo is positioned to translate groundbreaking science into durable clinical impact.

Our work culture is a hybrid model with 2 days/week in the New York City office and 3 days working from home.

Lexeo Therapeutics is an EEO employer committed to an exciting, diverse, and enriching work environment.

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