Scientist (Prion Electrophysiology)

(ID: 2025-1364)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations around the globe. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Benefits:

• 100% Medical, Dental & Vision Coverage for Employees

• Paid Time Off (Including Holidays)

• Employee Referral Bonus

• 401K Match

• Tuition reimbursement and professional development opportunities

• Flexible Spending Accounts:

• Healthcare (FSA)

• Parking Reimbursement Account (PRK)

• Dependent Care Assistant Program (DCAP)

• Transportation Reimbursement Account (TRN)

Overview

Axle is looking to add a driven, flexible, organized, and meticulous Scientist to our dynamic team. The Contractor(s) shall provide services in support of the overall functions of the Division of Intramural Research (DIR), Laboratory of Neurological Infections and Immunity (LNII).

Technical Requirements:

• Run and interpret multi-electrode array electrophysiology experiments on human brain organoids and other human alternative testing models and assist other lab members in similar experimental planning.

• Use murine brain slice cultures for investigation of prion pathogenesis and the function of the prion protein in health.

• Perform experiments with infectious human and animal prions practicing expert biosafety procedures.

• Liaise with the research technologies branch to create substantial high quality OMICs data across a broad range of technologies.

• Perform molecular imaging techniques, including confocal microscopy.

• Manage and maintain the prion electrophysiology suite.

• Provide upkeep and routine maintenance for projects, maintain laboratory supplies and equipment

• including chemicals, biological materials, etc., required to handle biological materials, recombinant protein materials, acids, biological wastes, etc., maintaining work bench and equipment related to projects.

• Catalog and label laboratory samples and consumables. Liaise with vendors as needed.

• Maintain detailed records of experiments and their results and prepare the information resulting from these experiments for presentations at laboratory-wide meetings and for publication.

• Write reports of findings, stating methods and procedures, including any modifications employed, specimens and materials involved and results of experiments. Interpreting, evaluating, and discussing the results of each experiment with the Federal Task Leader as part of the planning process for subsequent studies.

• Operate and communicate effectively in a group, team-oriented working environment. Work with and support others in a collegial, open, respectful, and interactive working manner. Work collaboratively with others in the lab to generate data for publications.

Specific Qualifications:

• Ph.D. in related field.

• Minimum five (5) years research experience with infectious prions and associated biohazards

• Expert experience with neuroelectrophysiology of human brain organoids and other new alternative models

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment-based age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: [email protected]

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individual’s assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$130,000—$140,000 USD