Scientist I, Nanoparticle Formulation and Process Development

GenEdit is an early-stage company that is developing a proprietary and novel delivery platform with the potential to transform genetic medicines. Our interdisciplinary team works together across polymer chemistry, payload, formulation, screening, and preclinical groups to develop the next generation of gene therapies and nanomedicines. We foster an exciting and dynamic environment where we value impactful data and creative solutions.

Job Description and Responsibilities
We are seeking a talented and motivated individual to join our team in Brisbane, CA, and support the development of genetic medicines utilizing GenEdit’s proprietary hydrophilic nanoparticle (HNP) platform. This position will work full-time in our wet labs to support nanoparticle formulation activities and will report to a scientist in our product and process development (PPD) team. This position will be expected to execute at a high level in the lab, keep detailed lab records, execute, optimize, and develop analytical techniques, and cooperate efficiently with other technicians and scientists.

Education and Qualifications
· PhD (or BS/MS with significant experience) in nanoparticle sciences and formulation
· 3+ years of relevant hands-on lab experience, ideally in an industry setting
· Required: expertise in nanoparticle formulation and related analytical characterization: optimization of mRNA and small molecule encapsulation mixing methods (IJM, microfluidics), light scattering and zeta potential (DLS, MALS), quantitative fluorescence assays (RiboGreen, fluorescamine)
· Highly preferred: nanoparticle scale-up manufacturing and process development including purification and concentration methods (TFF, UF/DF, sterile filtration, analytical HPLC) and standard molecular and cell biology techniques including UV-Vis, gel electrophoresis, protein expression characterization (western blot, ELISA, flow cytometry, FlowJo) and transfection of mammalian tissue culture
· Capable of independent experimental design, execution, and technical trouble shooting
· Ability to efficiently execute in the lab, develop standard operating procedures with precise reproducibility, and maintain detailed electronic lab notebook records
· Excellent communication, presentation, and organizational skills
· Work authorization in the US is required

At GenEdit we are always looking to hire the absolute best talent and recognize that diversity in our experiences and backgrounds is what makes us stronger. We hire candidates of any race, color, ancestry, religion, sex, national origin, sexual orientation, gender identity, age, marital or family status, disability, veteran status, and any other status. These differences are what enable us to work towards the future we envision for ourselves, and the world.