Scientist, Flow Cytometry (Contract)

Company Summary:

Quotient Therapeutics Ltd is a privately held, early-stage company developing a novel genomics platform and therapeutics for diseases with a large unmet need.

The company was founded by Flagship Pioneering, an innovative enterprise that conceives, creates, resources, and grows first-in-category life sciences companies. Flagship Pioneering has created over 100 groundbreaking companies over the past twenty years, all of which are pioneering novel and proprietary biological, industrial, and engineering approaches to solve major needs in human health and sustainability. These companies include Moderna (MRNA), Generate Biomedicines, Sana Biotechnology (SANA), Tessera Therapeutics, Evelo Biosciences (EVLO), Indigo Agriculture, Seres Therapeutics (MCRB), and Syros Pharmaceuticals (SYRS). We are an equal opportunity employer.

Position Summary:

We are seeking a motivated, enthusiastic Flow Scientist to join our passionate team. The role will take ownership of operating and maintaining flow cytometry and cell sorting equipment, as well as the design of flow panels and optimization of tissue dissociation and staining methods. The successful candidate will be a self-starter, able to thrive in a fast-paced, action-oriented team environment and have a clear passion for the science we are doing. They will have demonstrated evidence of agility in their scientific work and an overt attitude of positivity when facing challenges. They will be dedicated to learning and development, embrace feedback and be open to working outside their comfort zone.

Key Responsibilities:

• Operate, maintain and troubleshoot flow cytometry and cell sorting equipment, ensuring optimal performance for research activities.

• Design or adapt tissue dissociation and cell/nuclei isolation methods to meet project goals, and explore new technologies at the cutting-edge of the field.

• Design and validate antibody panels for flow cytometry and cell sorting.

• Conduct cell sorting to isolate specific cell populations, with high purity and viability.

• Assist in sample preparation of human tissues and cells.

• Provide technical support and training to other team members on the operation of flow cytometry and cell sorting equipment.

• Maintain compliance with regulatory requirements and quality standards, including the Human Tissue Act and COSHH.

• Collaborate and communicate with other team members across various functional areas.

Key Skills and Experience:

Essential

• BSc or MSc degree in biochemistry, molecular biology or microbiology, or a related field.

• A minimum of 5 years' hands-on experience of flow cytometry and cell sorting, including multispectral.

• Deep understanding of the maintenance and set up of flow cytometry and cell sorting equipment.

• Experience in the design and validation of antibody panels for flow cytometry.

• Knowledge and experience of working under HTA regulations.

• Excellent communication skills, both written and verbal.

• Use of laboratory information management systems (Benchling preferred).

Desirable

• Experience in the isolation and sorting of nuclei.

• Experience with optimization of tissue dissociation methods.

• Experience with next generation sequencing library preparation and other downstream molecular biology processing.

• Previous experience in a biotech or pharmaceutical industry setting.

• Experience working within a flow cytometry and cell sorting facility.

• Experience working with digital productivity tools such as Notion, Trello or Jira.

About Flagship

Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.

Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.