Scientist - Conjugation and Purification

About the role At AstraZeneca, we're embarking on an exciting new frontier in medical science – the quest to extend human health span . Our newly formed Aging Research Group is at the forefront of this groundbreaking initiative, aiming to develop innovative therapeutics that not only add years to life but life to years. Main Duties & Responsibilities: In this role, you will be part of a team of highly skilled and passionate individuals responsible for innovating and generating the best in class of antibody drug conjugates for various therapeutic areas. We are seeking a highly motivated conjugation scientist with a preferred background in drug discovery. Exciting opportunity to learn and contribute to multi-disciplinary drug development. Conjugation, purification and characterization of precursors for radio-conjugates (RC) and ADC using multiple validated methodologies Development and optimization of novel conjugation methodologies to improve RC and ADC properties Radiolabeling of RC for in vitro and biodistribution evaluations Collaborate and work with a diverse group of scientists across multiple therapeutic areas, chemistry, and process development to ensure timely progress in research projects and drive technological innovations Partner with colleagues on laboratory maintenance, including maintenance of equipment and lab safety. Education & Experience Requirements: Bachelor's or Master's degree in biotechnology , Pharmaceuticals Sciences, Chemical Biology, Biochemistry, Chemistry, or other relevant scientific field with 3 + years (BS degree) or 0-1 years (MS degree) of relevant experience. Required Skills: Hands-on experience and knowledge of protein purification using HIC, IEX, SEC and affinity chromatography. Experience with GE AKTA FPLC preferred. Working knowledge of characterization using analytical techniques like Hydrophobic Interaction Chromatography (HIC)-HPLC, Size Exclusion Chromatography (SEC), Liquid chromatography–mass spectrometry (LC-MS), Ion-Exchange (IEX), Reversed Phase (RP)-HPLC, etc. Proven ability to work independently, effectively plan and organize work activities and prioritize task completion to meet project deadlines Demonstrated experience in optimizing/troubleshooting protocols with a problem-solving mindset and maintains a detailed laboratory notebook Desired Skills: Demonstrated hands-on experience in the generation of RC and ADC . Experience with radiochemistry and related assays . Excellent written and verbal communication skills and effective presentation of complex scientific data to cross-functional and senior management . The annual base pay for this position ranges from $87,200 - $130,800. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans. Compensation Pay Range: 87,200.00 - 130,800.00 USD Annual The annual base pay (or hourly rate of compensation) for this position is outlined above. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. Date Posted 08-Jan-2026 Closing Date 30-Jan-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.