Scientific Director, Medical Information & Medical Communications

Company Overview

Tango Therapeutics is a biotechnology company dedicated to discovering novel drug targets and delivering the next generation of precision medicine for the treatment of cancer.

Using an approach that starts and ends with patients, Tango leverages the genetic principle of synthetic lethality to discover and develop therapies that take aim at critical targets in cancer.

This includes expanding the universe of precision oncology targets into novel areas such as tumor suppressor gene loss and their contribution to the ability of cancer cells to evade immune cell killing.

The Tango labs and offices are located at 201 Brookline Avenue, in the Fenway area of Boston, Massachusetts.

Summary

In this newly created role, the Scientific Director, Medical Information & Medical Communications will serve as a senior individual contributor within Medical Affairs, responsible for owning the medical information foundation and scientific narrative across Tango’s pipeline.

This role will be central to ensuring Tango is prepared to support increasing external engagement, regulatory interactions, congress presence, publications, and future commercialization. This is an exciting opportunity to shape foundational capability during a period of significant clinical and organizational inflection.

Your role

Medical Information Strategy & Operations

• Lead the end-to-end medical information strategy, including oversight of external MI vendors and call center operations

• Ensure timely, accurate, compliant, and evidence-based responses to external inquiries

• Develop, maintain, and govern medical information content, including SRLs, CRLs, FAQs, and response guidance

• Own medical information SOPs, KPIs, quality metrics, audit readiness, and inspection preparedness

• Ensure alignment with pharmacovigilance, regulatory, and compliance requirements

Scientific Narrative & Medical Communications

• Develop and maintain Tango’s core scientific platform and data narrative across indications and development stages

• Translate complex clinical, nonclinical, and mechanistic data into clear and compelling content for internal and external audiences

• Ensure consistency of scientific messaging across medical information, field materials, congress assets, and internal communications

Publications, Congress, & Content Governance

• Partner with Medical Affairs and Clinical teams to support publication planning and execution

• Oversee development of scientific materials for major medical congresses

• Provide medical information support at congresses, as appropriate

• Participate in the Medical Review process to ensure scientific accuracy, compliance, and data integrity

Cross-Functional Collaboration

• Collaborate closely with Medical Affairs leadership, Clinical Development, Regulatory Affairs, Corporate Communications, and Commercial (as appropriate and compliant)

• Ensure alignment between scientific communications, medical strategy, and enterprise objectives

• Perform additional duties as required to support Medical Affairs goals

What You Bring

• Advanced scientific degree required (PharmD, PhD, or MD strongly preferred)

• 7–10+ years of experience in Medical Affairs, Medical Information, or Scientific/Medical Communications

• Oncology experience strongly preferred; experience in GI malignancies, NSCLC, or precision oncology highly valued

• Experience in clinical-stage and/or pre-commercial biotech environments

• Exceptional scientific writing, editing, and data-positioning skills

• Strong understanding of clinical development, regulatory pathways, and medical affairs operations

• Demonstrated ability to manage vendors, agencies, and cross-functional stakeholders

• Experience with Veeva MedComms and PromoMats preferred

• Ability to operate effectively through ambiguity in a resource-constrained environment

• Excellent written and oral communication skills

Work Environment

• This role may be remote, with periodic travel to Tango offices and scientific meetings

• Approximately 10–20% travel

#LI-Remote

We are an equal opportunity employer and value diversity at our company. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Salary range
$187,200—$280,800 USD