Scientific Associate I

UHN is Canada’s #1 hospital and the world’s #1 publicly funded hospital. With 10 sites and more than 44,000 TeamUHN members, UHN consists of Toronto General Hospital, Toronto Western Hospital, Princess Margaret Cancer Centre, Toronto Rehabilitation Institute, The Michener Institute of Education and West Park Healthcare Centre. As Canada's top research hospital, the scope of biomedical research and complexity of cases at UHN have made it a national and international source for discovery, education and patient care. UHN has the largest hospital-based research program in Canada, with major research in neurosciences, cardiology, transplantation, oncology, surgical innovation, infectious diseases, genomic medicine and rehabilitation medicine. UHN is a research hospital affiliated with the University of Toronto.

UHN’s vision is to build A Healthier World and it’s only because of the talented and dedicated people who work here that we are continually bringing that vision closer to reality.

www.uhn.ca

Union: Non- Union

Number of Vacancies: 1

New or Replacement Position: Replacement

Site: Princess Margaret Research, MaRS South Tower

Department: UHN Research

Reports to: Principal Investigator

Salary Range: $72,185 - $90,222 Annually

Hours: 37.5 Hours Per Week

Shifts: Monday - Friday

Status: Temporary Full-time (1 Year Contract)

Closing Date: March 13, 2026

Position Summary:

The Scientific Associate I will work within an exciting new multidisciplinary international research project which seeks to accelerate the early stages of drug discovery. Reporting to the Co-Director of the UHN Collaborative Centre for Drug Discovery, the Scientific Associate IV will lead a research team working on affinity selection mass spectrometry (ASMS), and coordinate activities with collaborating research teams in protein science, novel compound screening technologies, protein interaction characterization, medicinal chemistry, data science, and AI/machine learning. We work closely with academic institutions, pharmaceutical companies, and technology leaders to develop innovative tools and platforms that make biomedical research faster, more collaborative, and more impactful. This open science, milestone-driven program seeks to revolutionize and democratize drug discovery to advance human health.

Apply now and help us redefine how new medicines are discovered!

Duties:

• Coordinate ASMS logistics: project set-up, scheduling of ASMS experiments, and workflows involving proteins, compounds, and reagents from different sources.
• Coordinate flow of data output and ensure prompt and accurate deposition in Project databases.
• Coordinate with peer coordinators in protein production, hit characterization and database teams, to receive proteins, share hit data and upload the data to the AIRCHECK database.
• Ensure details of any detected ASMS hits will be communicated with the hit characterization team for biophysical validations.
• Track ASMS data submissions internally and externally, maintain the central database, and organise project progress meetings.
• Coordinate with protein production, database and hit validation teams to ensure timely feedback to contributors.
• Prepare regular reports, KPIs, and dashboards for leadership, funders, and collaborators.
• Identify workflow bottlenecks and work with team to implement process improvements.
• Contribute to project planning, resource allocation, risk management, and budgeting.
• Foster collaboration across the global team through leadership, problem-solving, and conflict resolution.

• PhD in analytical chemistry, biochemistry, or relevant scientific field, or equivalent combination of education.
• Minimum three (3) years of demonstrated research experience in biochemistry and drug discovery
• Strong expertise and knowledge in molecular biology and mass spectrometry
• Experience preparing manuscripts for submission to peer review publications/journals
• Strong publication record on mass spectrometry, analytical chemistry or protein chemistry
• Experience presenting results and conclusions at meetings or conferences
• Excellent research and analysis skills.
• Strong oral and written communication skills
• Excellent skills of science communications
• Ability to work independently and as part of a team in a fast-paced environment
• Willingness and ability to travel for conferences, meetings, and site visits.

Why join UHN?

In addition to working alongside some of the most talented and inspiring healthcare professionals and researchers in the world, UHN offers a wide range of benefits, programs and perks. It is the comprehensiveness of these offerings that makes it a differentiating factor, allowing you to find value where it matters most to you, now and throughout your career at UHN.

• Competitive offer packages
• Government organization and a member of the Healthcare of Ontario Pension Plan (HOOPP https://hoopp.com/)
• Close access to Transit and UHN shuttle service
• A flexible work environment
• Opportunities for development and promotions within a large organization
• Additional perks (multiple corporate discounts including: travel, restaurants, parking, phone plans, auto insurance discounts, on-site gyms, etc.)

Current UHN employees must have successfully completed their probationary period, have a good employee record along with satisfactory attendance in accordance with UHN's attendance management program, to be eligible for consideration.

All applications must be submitted before the posting close date.

UHN uses email to communicate with selected candidates.  Please ensure you check your email regularly.

Please be advised that a Criminal Record Check may be required of the successful candidate. Should it be determined that any information provided by a candidate be misleading, inaccurate or incorrect, UHN reserves the right to discontinue with the consideration of their application.

UHN is an equal opportunity employer committed to an inclusive recruitment process and workplace. Requests for accommodation can be made at any stage of the recruitment process. Applicants need to make their requirements known.

We thank all applicants for their interest, however, only those selected for further consideration will be contacted.