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Science Program Analyst

Axle

Bethesda, MD (Axle Informatics LLC) permanent

Posted: December 24, 2025

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Job Description

(ID: 2025-1301)

Axle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).

Axle is seeking a Science Program Analyst to join our vibrant team at the National Institutes of Health (NIH) supporting the Office of the Director (OD) located in Bethesda, MD.

Benefits We Offer:

• 100% Medical, Dental & Vision Coverage for Employees

• Paid Time Off and Paid Holidays

• 401K match up to 5%

• Educational Benefits for Career Growth

• Employee Referral Bonus

• Flexible Spending Accounts:

• Healthcare (FSA)

• Parking Reimbursement Account (PRK)

• Dependent Care Assistant Program (DCAP)

• Transportation Reimbursement Account (TRN)

Position Summary & Objectives

• Gather, organize, and analyze quantitative and qualitative data to support NIH efforts to:

• Prioritize human-based research

• Reduce and replace animal use in biomedical research, drug development, and regulatory testing

• Use Large Language Models (LLMs) and other AI tools, as appropriate, to streamline portfolio analysis and report development

• Track and analyze legislative, policy, and scientific developments related to human-relevant, non-animal research methods

• Attend, summarize, and report on meetings related to human-relevant, non-animal methodologies

• Prepare briefings, reports, slide presentations, and talking points for senior leadership within DPCPSI/NIH

Key Responsibilities & Deliverables

• Gather, organize, and analyze data supporting NIH initiatives to advance human-based research approaches (Highest Priority)

• Track legislative, policy, and scientific advances related to non-animal research models and integrate findings into reports and presentations

• Develop slide decks and talking points promoting NIH initiatives to adopt human-based methods and reduce animal use

• Draft briefs, reports, and other written materials for NIH senior leadership

• Use LLMs and AI tools, as appropriate, for data analysis and preparation of briefing documents

• Support cross-agency collaborations with:

• Federal partners

• Research institutions

• Private-sector innovators
to foster a collaborative culture around non-animal research and testing

• Produce detailed analytical reports for use by upper management

Program & Evaluation Support

• Provide technical expertise in evaluating programs related to non-animal research initiatives

• Work with Evaluation Subject Matter Experts (SMEs) within DPCPSI/OEPR and the DPCPSI Director’s Office to:

• Identify effective programs and policies advancing non-animal research methods

• Contribute to evaluation efforts using established metrics

• Collect and analyze internal data

• Assist in drafting evaluation summaries and recommendations

Technical Skills

• Environmental science or related scientific discipline

• Data science and portfolio analysis

• Computational toxicology

• Novel alternative (non-animal) research methodologies

• Large Language Models and AI-enabled analysis tools

Professional Skills

• Strong report and technical writing

• Policy and legislative analysis

• Quantitative and qualitative data analysis

• Presentation development (briefings, slides, talking points)

Software Proficiency

• Microsoft Word, Excel, and PowerPoint

Disclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.

The diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.

Accessibility: If you need an accommodation as part of the employment process please contact: [email protected]

This role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.

Salary Range
$85,000—$92,000 USD

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