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Regional Business Director, Sunosi (Appalachia Region)

Axsometherapeutics

Nashville, TN (Field-Based) permanent

Posted: May 13, 2026

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Quick Summary

The Regional Business Director will be responsible for leading commercial activities in the Appalachian Region, establishing a team of Account Managers, executing marketing strategies, and ensuring a successful launch.

Job Description

Axsome Therapeutics, Inc. is a biopharmaceutical company developing and delivering novel therapies for the management of central nervous system (CNS) disorders. The Axsome team is a lean, dynamic group of individuals committed to addressing unmet needs for patients with CNS disorders. Axsome is based in New York City.

About This Role

Axsome Therapeutics is currently searching for a Regional Business Director (RBD) to lead commercial activities for an assigned geography, establish a team of Account Managers, execute marketing strategies, and ensure a successful launch. The RBD will be primarily responsible for the supervision and leadership of an industry shaping, uniquely structured salesforce leveraging the use of a highly sophisticated digital infrastructure. All sales representatives will be aligned to geographical boundaries.

The RBD is responsible for sales performance at a Region level and is expected to be a product champion and exhibit the business knowledge of the local landscape to assess key stakeholders plus future trends within the marketplace. This is a cross-functional front-line leader role that will focus on Sunosi (solriamfetol), which is indicated to improve wakefulness in adults with excessive daytime sleepiness due to obstructive sleep apnea or narcolepsy. The position is field-based and will require travel as needed to develop internal and external relationships.

Job Responsibilities and Duties include, but are not limited to, the following:

• Responsible for supervising operations of the Region which includes: driving results, hiring and coaching, account manager development, performance management, and the assignment of key "priority" accounts within the medical community

• Develop and implement strategic plans for the Region including the right balance of live/virtual interactions and the prioritization of efforts by the team

• Plan, organize and drive performance to achieve the business potential of the region through coaching and influence of direct reports

• Establish and maintain effective communication among all members of the Region across cross-channel stakeholders in the Accounts and Market Access team

• Maintain required technical expertise in order to respond accurately to all questions regarding products, marketing, policies, and business-related issues from customers and account managers

• Work with direct reports to understand and consistently execute established expectations.

• Consistently exemplify the ability to help a SAM improve on their selling skills, product knowledge and capabilities needed for success through coaching and counsel. Lead by example through coaching direct reports both in live and virtual engagements.

• Effectively plan and conduct plan of action and other meetings with members of the Region and Market Access teams 

• Develop and implement Region business plan, manage Region budget and overall responsibility for P&L at Region level in alignment with Regional and National expectations

• Have a complete understanding of all relevant compliance laws, policies and processes and ensure actions of self and team are fully compliant

• Overnight travel as indicated by the needs of the business

• Additional responsibilities as assigned

Qualifications / Requirements

• BA or BS required. Advanced degree preferred

• 5 years or more of field leadership experience and/or payer account management and/or demonstrated sales success with increasing responsibility and organizational leadership

• Previous pharmaceutical, biotech, or medical marketing/sales experience preferred with at least three to five years spent in a position with demonstrated 1st line leadership groups

• Proven performance history in the ability to lead others to success through your coaching influence

• Demonstrated experience delivering outstanding results and developing others to their potential

• Proven track record in attracting and retaining top talent

• Current or recent sleep/CNS experience strongly preferred

• Successful launch experience strongly preferred

• Experience to strategize within teams using differential resources to reach business goals

• Proven ability to run multiple tasks concurrently under aggressive timelines in a dynamic environment

• Must live within the territory’s geography

• Comfortable with uncertainty and high expectations

• Patient support services experience a plus

• Strong digital marketing aptitude

• Strong interpersonal and presentation skills

Salary & Benefits

The anticipated salary range for this role is $165,000 - $205,000. We encourage candidates of all levels to apply as there may be flexibility on final job title and responsibilities. The salary offer will be based on a variety of factors, including experience, qualifications, internal equity and location. Axsome offers a competitive employment package that includes an annual bonus, significant equity and a generous benefits package.

Axsome is committed to equal employment opportunity and providing reasonable accommodations to applicants with physical and/or mental disabilities. We value and encourage diversity and solicit applications from all qualified applicants without regard to race, color, gender, sex, age, religion, creed, national origin, sexual orientation, gender identity, ancestry, citizenship, marital status, physical or mental disability, medical condition, veteran status, genetic information, or any other characteristic protected by federal, state, or local law.

Axsome Therapeutics does not accept unsolicited resumes from recruiters or third-party recruitment agencies and will not pay placement fees for unsolicited candidates that are sent to hiring managers, the HR team or other Axsome team members. Only approved vendors who have been explicitly asked to support a specific search will receive access to our Applicant Tracking System to submit candidates for consideration.

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