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Quantitative Systems Pharmacology Modeler - all genders

Sanofi

Frankfurt am Main permanent

Posted: March 24, 2026

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Quick Summary

The Disease Modeling department at Sanofi is seeking a highly talented mathematical modeling scientist to support its R&D portfolio. The role involves developing and implementing complex mathematical models to simulate and analyze the behavior of biological systems. The successful candidate will work on various projects to speed up drug discovery and development.

Job Description

About the job

The Disease Modeling department at Sanofi is seeking for a highly talented mathematical modeling scientist to support its R&D portfolio. The Disease Modeling group is part of the Translational Medicine Unit in Sanofi R&D. At Sanofi, a global health care and pharmaceutical company, modeling & simulation approaches support critical decision making throughout the various phases of drug discovery and development.

Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress. Join our Disease Modeling team as Quantitative Systems Pharmacology Modeler (all genders) and you’ll actively help shape the future for our immunology & inflammation portfolio.

About Sanofi:

We’re an R&D-driven, AI-powered biopharma company committed to improving people’s lives and delivering compelling growth. Our deep understanding of the immune system – and innovative pipeline – enables us to invent medicines and vaccines that treat and protect millions of people around the world. Together, we chase the miracles of science to improve people’s lives.

Main responsibilities:

• Generation and application of Quantitative Systems Pharmacology (QSP) models and virtual patients in close collaboration with multidisciplinary teams to drive decision making in pharmaceutical research and development.
• Run in-silico clinical trials in virtual patients to de-risk, optimize, and accelerate drug development.  
• Modeling and simulation expert in research and clinical development teams with experts from different functional areas.
• Assessment and prioritization of modeling needs and contribution to strategic modeling work plans for R&D projects to ensure quality and impact of modeling and simulation work packages.
• Clear communication of modeling results to key stakeholders.
• Implementation of scientific and technological innovations in the area of QSP and disease modeling.

About you

Experience:

• 3+ years of mathematical modeling & computer simulation experience specific for biomedical/pharmaceutical applications (experience within pharmaceutical industry highly desired).

Soft and technical skills:

• Broad understanding of disease, disease progression and pharmacology for respective therapeutic area (experience within immunology and inflammation desired).
• Good understanding of cell biology and physiology as well as understanding of the basic principles of pharmacokinetics and pharmacodynamics required.
• Hands-on experience with programming languages like Matlab/Julia. Knowledge of C/C++/Python/R desirable.
• Strong communication skills as well as desire to work within an interdisciplinary team environment.

Education:

• Ph.D. in Biomedical Engineering, Systems Biology/Pharmacology, Applied Mathematics or related fields.

Languages:

• Proficient in spoken and written English

Why choose us?

• Be part of a pioneering biopharma company that engages patients early in drug development and uses their insights to design studies that reflect real-world needs. 

• Work at the forefront of drug discovery, harnessing cutting-edge AI, data, and digital platforms to push the boundaries of science. 

• Help improve the lives of millions of people globally by making drug development quicker and more effective. 

• Enjoy opportunities to collaborate beyond your area of expertise, working with diverse teams across science, clinical, and digital fields to spark new ideas and drive breakthroughs. 

• Accelerate your professional development with structured career paths designed for both scientific and leadership advancement. Grow in ways you never imagined through bold moves that stretch your potential, cross moves into other business areas, and short-term gigs that build your scientific expertise.​     ​

• Join a workplace where diversity, equity, and inclusion are at the core, with Employee Resource Groups and leadership programs that celebrate every voice.

• Enjoy outstanding benefits, including flexible working options, comprehensive healthcare, and well-being programs designed to help you thrive.

#LI-Hybrid

#QuantitativeSystemsPharmacology

#VirtualPatients

#ClinicalTrials

#CellBiology

#Sanofi

#SanofiCareers

#PursueProgress

#DiscoverExtraordinary

#IgnitingPotential

Pursue progress, discover extraordinary

Better is out there. Better medications, better outcomes, better science. But progress doesn’t happen without people – people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let’s be those people.

At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.

Watch our ALL IN video and check out our Diversity Equity and Inclusion actions at sanofi.com!

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