Project Manager, Late Stage Programs

Arrowhead Pharmaceuticals, Inc. (Nasdaq: ARWR) is a clinical stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead’s RNAi-based therapeutics leverage this natural pathway of gene silencing.

Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates.

Arrowhead’s corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need.

The Position

The Project Manager is an integral part of several Product Teams developing novel RNAi therapeutics for diseases with high unmet need. The Project Manager will work under the Senior Director, Program Management to define and monitor timelines and deliverables. The successful Project Manager will have excellent knowledge in Smartsheet and other program planning and visualization software, good communication skills and enthusiasm for defining and monitoring program plans and milestones at Arrowhead Pharmaceuticals.

This role is based in Pasadena, California, with an expectation to be in office 5 days a week.

Responsibilities

• Drive cross-functional collaboration to develop and manage integrated late-phase program plans and timelines

• Facilitate and document meetings, capturing and tracking key decisions, action items, and follow-ups

• Prepare and deliver presentations, reports, and events to align and engage stakeholders

• Develop scenario planning models and visualizations to support strategic and operational decisions

• Coordinate across Product and Work Package Teams with diverse technical and functional backgrounds

• Standardize and communicate program timelines across teams and the broader portfolio

• Manage resources and budgets using Smartsheet or equivalent planning and visualization tools

• Monitor progress, track deliverables, and proactively identify and escalate risks to Program Leadership

• Maintain dashboards, portfolio updates, and enterprise-level progress reports

• Support special projects as needed including workshop facilitation to vendor assessments

• Collaborate within a matrixed organization to integrate program timelines, resolve bottlenecks, and ensure cross-program alignment

Requirements:

• Bachelor's degree in a business-related or life sciences field

• Strong understanding of the life sciences industry

• 5 years of project planning or coordination experience in biotech, pharmaceuticals, or medical devices

• Strong foundation in program and project management principles

• Proven ability to understand complex interdependencies and maintain attention to detail

• Demonstrated experience leading or coordinating cross-functional teams

• Excellent communication, influencing, stakeholder management, and decision-making skills

• Highly motivated team player with a proactive, collaborative approach

• Thrives in a dynamic, growing biotech or early commercial-stage environment

California pay range
$110,000—$125,000 USD

Arrowhead provides competitive salaries and an excellent benefit package.

All applicants must have authorization to work in the US for a company.

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