Project Manager, Cell Therapy Business Systems

In AstraZeneca's Cell Therapy division, we follow the science to explore and innovate. We are working towards treating, preventing, modifying, and even curing some of the world's most complex diseases. We have the potential to grow our pipeline and positively impact the lives of patients around the world. The Project Manager, Cell Therapy Business Systems will lead digital and enterprise systems projects critical to the manufacturing, logistics, and quality operations of cell therapy products. This Associate Director-level role is located in either Santa Monica, CA, or Gaithersburg, MD. You will report to the Head of Business Planning and Operations and collaborate with the Director of Business Systems to ensure the effective execution of projects.

You Will:

• Lead end-to-end implementation and enhancement of enterprise systems (such as cell orchestration platform) supporting cell therapy supply chain and manufacturing.

• Be the bridge between IT, operations, and external vendors to ensure system capabilities meet business needs

• Define project scope, timeline, resources, and milestones for system initiatives

• Manage matrix project teams and drive execution of project priorities

• Coordinate user requirements, testing, validation, documentation, and business deployment activities

• Ensure project understanding of Chain of Identity (COI), Chain of Custody (COC), Plan-To-Make, Order-To-Cash, and regulatory requirements and internal policies processes

• Create detailed project or business plans to manage project scope, deliverables, releases, risks and mitigations

• Support development of long range plans for system innovations / enhancements according to business strategy

• Coordinate development of project readouts to governance and senior leadership

• Track project KPIs and report to senior leadership, including risk mitigation and change management updates.

• Manage the project information repository

• Manage the project budget

• Manage the identification and escalation of potential issues/risks or obstacles

• Lead change management efforts to improve adoption of new products and technology solutions, providing training, support, and communication partners at all levels.

• Communicate and build relationships with a broad spectrum of audiences at all organizational levels.

You Have:

• Eight (8) years with BS/BA, or six (6) years with MS/MA, in Life Sciences, Biotechnology, in Information Technology, Computer Science, Engineering, or a related field.

• Experience in cell and gene therapy is preferred.

• Experience with all phases of project management, with expertise across a variety of technology project areas in supply chain, manufacturing, quality operations, and clinical systems.

• Knowledge of supply chain and cell therapy workflows.

• Proven track record in any of the following applications: Cell orchestration, ERP, MES, or LIMS

• Project management certification (PMP) is desired.

• Experience with project management tools (e.g. MS Project, Smartsheet)

• Experience working with matrix teams and managing complex programs in a regulated and enterprise level.

The annual base salary for this position ranges from $120,152 to $180,229. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles).

Our Benefits:

• A qualified retirement program [401(k) plan]

• Paid vacation, holidays, and paid leaves

• Health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment.

#celltherapy #LI-Onsite

We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender, gender identity or expression, or veteran status. We are proud to be an equal opportunity workplace.

Date Posted

13-Feb-2026

Closing Date

26-Feb-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.