Principal Quantitative Scientist

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

Who we are

Roche Diagnostics has built a new strategic area – Roche Information Solutions (RIS) - charged with creating a modern portfolio of decision support software products and generating insights that change the way patients are cared for. Our challenge is to bring together complex diagnostic and treatment data from medical devices and IT systems and intelligently process and present this data to clinicians, researchers, and caregivers to improve research outcomes and patient care by offering a suite of Clinical Decision Support (CDS) solutions.

The Opportunity

As a Principal Quantitative Scientist, you will act as a scientific leader for Real-World Data (RWD), driving evidence generation that fundamentally shapes the development and adoption of our digital health, IVD. This is a high-impact, independent role requiring deep expertise and the ability to influence critical business and regulatory decisions. Your work will involve leveraging diverse data types, including EHR, claims, omics, and digital health data.

Key responsibilities include:

RWD Strategy & Execution (End-to-End Leadership)

Drive the conceptualization, planning, execution, and reporting of advanced RWD studies using various research and commercial healthcare databases.

Develop rigorous RWD study protocols and lead complex analyses to support the evidence needs of the IVD and digital health portfolio.

Ensure the design, execution, and presentation of RWE adhere to the highest scientific and methodological standards.

Strategic Influence & Adoption

Act as a RWD leader, working closely with cross-functional stakeholders such as Product Leads and Medical Affairs to ensure RWD projects directly support commercial, market access, and regulatory needs.

Champion RWD's use to supplement clinical evidence and actively identify opportunities where RWD can serve as the primary evidence mechanism to achieve regulatory and reimbursement objectives.

Collaborate with external partners (KOLs, academic institutions, healthcare authorities) on study design and foster strong relationships to explore new data assets and analytical methodologies

Expertise & Mentorship:

Leverage and expand expertise in RWD sources, epidemiology, and state-of-the-art causal inference methodologies.

Promote innovation by enhancing ways of working (processes, methods, technology) and proactively sharing learnings with peers.

Mentor junior colleagues and act as an influential subject matter expert to the team.

Who You Are

You hold a PhD (preferred) OR Master’s Degree in a Quantitative science field (e.g. Pharmacoepidemiology, Epidemiology, RWD Biostatistics, Pharmacoeconomics, Health Economic and Outcomes Research)

And 7+ years of directly related (industry, consulting, or other relevant) experience.

Proven track record of utilizing RWD to support regulatory submissions.

Solid expertise in epidemiology and causal inference methodologies is required.

Strong programming experience with R, Python, SQL and/or other quantitative software.

Strong experience in using diverse RWD sources to generate insights and evidence.

Additional Skills:

Expertise in RWD & Epidemiology: Proven hands-on experience in designing, implementing, and reporting RWD studies, with specific expertise in epidemiology and a passion for making a difference in healthcare.

Strategic & Regulatory Acumen: A solid understanding of regulatory guidelines and an ability to use RWD to influence national and international reimbursement and clinical guidelines.

Project & People Leadership: Strong project management skills, including the ability to manage scope and delegate. You are a recognized team leader with experience mentoring team members and possess a resilient, can-do attitude.

Communication & Collaboration: Excellent communication and collaboration skills, including the ability to influence others without formal authority. A professional working proficiency in English is required.

Problem-Solving & Mindset: A data-savvy, creative, and resilient problem solver with a sense of ownership and attention to detail. You are eager to learn and expand your scientific expertise as a reliable team player and thought partner.

Location: Sant Cugat (Hybrid model)

Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.

Roche is an Equal Opportunity Employer.