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Pi Historian and Integration Technical Manager

AstraZeneca

US - Frederick - MD permanent

Posted: January 4, 2026

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Job Description

Our Frederick Manufacturing Center (FMC) creates life-changing medicines for people around the world and has been recognized by our local community as being a Top 50’ Business in Frederick and awarded Frederick County’s ‘Best Place to Work’. This distinctive biologic manufacturing facility, with over 800 employees, makes a direct contribution to treating people with cancer, respiratory and autoimmune conditions across the globe. We work hard to deliver life-changing medicines to patients, and we take time to have fun and celebrate our accomplishments. From catered site festivities to competitive events, community outreach activities, environmental and wellness showcases and team-building functions, we take time to recognize our achievements and celebrate our diversity. We are dedicated to creating a culture of inclusion and collaboration and are committed to continuous learning by offering ongoing skill building and training for our staff. Fueled by our aspiration to deliver accelerated growth for our company and to make people’s lives better, there’s never been a more exciting time to join the team and shape the future of AstraZeneca Operations Are you ready to lead the charge in transforming how we manage data and integrations? As the Pi Historian and Integration Technical Manager, you'll be at the forefront of ensuring seamless connectivity and data management within FMC’s Aveeva Pi Historian, PAS|X integrations, and Operations Data Hub. This pivotal role involves overseeing system ownership, driving change management, and providing expert guidance on best practices for historian and integration processes. Your leadership will be crucial in aligning data frameworks and supporting ongoing revisions to enhance operational efficiency. Accountabilities: • Lead the team in identifying technical solutions from business requirements for PAS|X, SIMCA, and Tulip integrations. • Collaborate with cross-functional groups to meet project timelines and company goals. • Align technical solutions across IT, Facilities, PAS|X, Automation, external vendors, and interfaces. • Ensure compliance with operations best practices and GxP requirements. • Provide training and hands-on experience for IT and Site resources with the Historian application. • Prototype technical approaches and oversee validation of technical solutions. • Establish best practices for knowledge and lifecycle management of Pi Historian and ODH. • Track and complete documentation related to technical work. • Manage frequent changes in scope, timeline, and priority. • Make informed decisions using technical knowledge. • Meet project goals within time and budget constraints. • Recommend technologies for company pursuit. • Mentor and guide junior team members. • Demonstrate strong critical thinking and problem-solving skills. • Work independently and within team environments with strong communication abilities. • Display eagerness to learn new tools, software, and technologies. Essential Skills/Experience: • Bachelor's degree in a technical field • Over 5 years of work experience in integration and Historian software administration • Proficient in biologics manufacturing use of Historian and integration into PAS|X and ODH (or similar) Desirable Skills/Experience: • Bachelor’s degree in engineering or computer science • 7+ years of experience in the automation or applied engineering field At AstraZeneca, technology is a key lever in delivering medicines quickly, affordably, and sustainably. We embrace change by trialing new solutions with patients and business needs in mind. Our diverse workforce is united by curiosity, sharing learnings to scale fast. Be part of our digital journey as we impact all parts of the business, from smart factories to machine learning for quality batches. Join us in delivering life-changing medicines while making a bigger impact on society, the planet, and our business. Ready to make a difference? Apply now to join our team! The annual base pay (or hourly rate of compensation) for this position ranges from $129,516.80 to $194,275.20 Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors Date Posted 17-Dec-2025 Closing Date 22-Jan-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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